Objective: To investigate and compare the synchronous metastasis distribution of sarcomatoid renal cell carcinoma(SRCC) and clear cell renal cell carcinoma(CCRCC), so as to contribute to their differential diagnosis. Methods: Synchronous metastasis means metastasis at the time of diagnosis. A retrospective analysis of the medical records and imaging data of 45 SRCC and 143 CCRCC which diameter larger than 6 cm, all the cases had their preoperative abdominal enhancement CT, analysis their synchronous metastasis distribution by χ2 or Fisher’s exact test. Results: There were 16 SRCC and 10 CCRCC had synchronous metastasis(16/45 vs 10/143), 11 SRCC and 1 CCRCC had synchronous lymph node metastasis(11/45 vs 1/143), 6 SRCC and 6 CCRCC had synchronous lung metastasis(6/45 vs 6/143), 6 SRCC and 1 CCRCC had multiple synchronous metastasis(5/45 vs 1/143), and the differences were statistically significant(P=0.000, 0.000, 0.039, 0.003). However, only synchronous lymph node metastasis remained statistically significant(P=0.030) by Logistic regression. Conclusion: Synchronous lymph node metastasis can help to discriminate SRCC and CCRCC, as this feature is more common in SRCC.
Key words
Kidney neoplasms /
Neoplasm metastasis /
Tomography, X-ray computed
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