Clinical value of double phase 99mTc-MIBI imaging in diagnosing hyperparathyroidism

CHEN Wei-an; CUI Ying-peng; LI Chun-yi; LIANG Hong; HU Ping

Journal of China Clinic Medical Imaging ›› 2006, Vol. 17 ›› Issue (3) : 146-147.

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Clinical value of double phase 99mTc-MIBI imaging in diagnosing hyperparathyroidism

CHEN Wei-an, CUI Ying-peng, LI Chun-yi, LIANG Hong, HU Ping

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Abstract

Objective: To evaluate the clinical value of double phase 99mTc-MIBI imaging in diagnosing hyperparathyroidism. Methods: Forty-four patients with highly suspected hyperparathyroidism underwent double phase 99mTc-MIBI imaging. Abnormal increase radioactivity in delay imaging stood for positive index. Imaging material were evaluated according to final clinical results and compared with ultrasound or CT. Results: In 44 patients, 33 hyperparathyroidism were proven, including 31 adenomas(ectopic 1), 1 hyperplasia and 1 carcinoma. The sensitivity and specificity of diagnosis were 90.9%, 100%, respectively. The accuracy of double phase 99mTc-MIBI imaging was 93.2%. The sensitivity and specificity of ultrasound were 70%, 77.3%, respectively. The sensitivity of CT was 60%. The results showed that double phase 99mTc-MIBI imaging was superior to ultrasound and CT(P<0.05). Conclusion: Double phase 99mTc-MIBI imaging could accurately diagnose hyperparathyroidism. It is an important localizing method for preoperation which is worthy of generating.

Key words

hyperparathyroidism / radionuclide imaging / ultrasonography / tomography / X-ray computed

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CHEN Wei-an;CUI Ying-peng;LI Chun-yi;LIANG Hong;HU Ping. Clinical value of double phase 99mTc-MIBI imaging in diagnosing hyperparathyroidism[J]. Journal of China Clinic Medical Imaging. 2006, 17(3): 146-147