Diagnosis of MRI in lipid storage myopathy

ZHENG Xian-ying; MURONG Shen-xing; LI Yin-guan; NI Xi-he; CAO Dai-rong

Journal of China Clinic Medical Imaging ›› 2006, Vol. 17 ›› Issue (8) : 458-460.

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Diagnosis of MRI in lipid storage myopathy

ZHENG Xian-ying, MURONG Shen-xing, LI Yin-guan, NI Xi-he, CAO Dai-rong

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Abstract

Objective: To investigate MRI findings of lipid storage myopathy(LSM), and evaluate the clinical value of MRI for LSM. Materials and Methods: Nine cases with LSM proved by biopsy underwent MRI of pelvis and thigh, spin echo sequence, fast spin echo sequence and short tau inversion recovery(STIR) were used. Results: The signal intensity of diseased muscle in 8 cases with LSM was hyperintense on T2WI and T1WI, and hyperintense signal intensity on T2WI and iso-intense on T1WI was seen on 2 patients as well. One patient had no positive findings. Conclusion: The MRI findings in LSM show certain characteristics: the involved muscles show lipid storage findings symmetrically, and the necrotic-like signal can be seen in the active stage as well. MRI can provide objective data for clinical diagnosis, therapeutic evaluation and follow-up. It can also help to decide the accurate site for biopsy.

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muscular diseases / magnetic resonance imaging

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ZHENG Xian-ying;MURONG Shen-xing;LI Yin-guan;NI Xi-he;CAO Dai-rong. Diagnosis of MRI in lipid storage myopathy[J]. Journal of China Clinic Medical Imaging. 2006, 17(8): 458-460