Value of 18F-FDG PET/CT in diagnosing the unknown cause of ascites

TAN Hai-bo; YAN Jin; ZHAO Jun; GUAN Yi-hui; HUA Feng-chun; ZUO Chuan-tao; ZHANG Zheng-wei; WANG Hong-bing; LIN Xiang-tong

Journal of China Clinic Medical Imaging ›› 2008, Vol. 19 ›› Issue (3) : 178-180.

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Value of ¹⁸F-FDG PET/CT in diagnosing the unknown cause of ascites

TAN Hai-bo, YAN Jin, ZHAO Jun, GUAN Yi-hui, HUA Feng-chun,
ZUO Chuan-tao, ZHANG Zheng-wei, WANG Hong-bing, LIN Xiang-tong

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Abstract

Objective: To evaluate the diagnostic value of 18F-FDG PET/CT for the patients with ascites of unknown causes. Methods: Twenty-two patients with ascites of unknown cause refered to our department for whole-body 18F-FDG PET/CT. The causes of their ascites could not be confirmed by ultrasound, endoscope and/or radiographic imaging, CT and/or MRI, and diagnostic paracentesis for biochemical content and cytology. The images were interpreted by visual inspection and semi-quantitative analysis(standardized uptake value, SUV). Results: According to the results of follow-up and pathology, 14 patients were confirmed as malignant ascites, 4 ascitic patients were caused by other reasons, the causes of ascites were still unknown in 4 patients. In the 14 patients of malignant ascites, in 7 patients primary focus were found by 18F-FDG PET/CT and 7 patients were false negative. 10/22 cases(45.5%) were correctly diagnosed. Conclusions: 18F-FDG PET/CT was a more sensitive and effective method in finding the causes of ascites compared with traditional imaging methods.

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Ascites / Radionuclide imaging

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TAN Hai-bo;YAN Jin;ZHAO Jun;GUAN Yi-hui;HUA Feng-chun;ZUO Chuan-tao;ZHANG Zheng-wei;WANG Hong-bing;LIN Xiang-tong. Value of ¹⁸F-FDG PET/CT in diagnosing the unknown cause of ascites[J]. Journal of China Clinic Medical Imaging. 2008, 19(3): 178-180