Experimental study on lipid ultrasound contrast agent in imaging and differentiating renal VX2 carcinoma

ZENG Gong-jun; LIU Jian-hua; GAO Yun-hua; LIU Zheng; TAN Kai-bin; WU Mei

Journal of China Clinic Medical Imaging ›› 2008, Vol. 19 ›› Issue (6) : 412-414.

论著

Experimental study on lipid ultrasound contrast agent in imaging and differentiating renal VX2 carcinoma

ZENG Gong-jun1, LIU Jian-hua1, GAO Yun-hua2, LIU Zheng2, TAN Kai-bin2, WU Mei1

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Abstract

Objective: To evaluate the imaging capability of lipid ultrasound contrast agent in imaging and differentiating renal VX2 carcinoma. Methods: Fourteen rabbits with VX2 carcinoma of left kidney were scanned by fundamental imaging and second harmonic imaging(SHI) after bolus injection of lipid ultrasound contrast agent(Zhifuxian 0.02ml/kg). The contrast-enhanced effect was estimated with qualitative vision and quantification gray-scale value. Results: The tumor was enhanced 5s after injection of ultrasound agent and lasted for 10~15 minutes. As to the qualitative vision there was statistically significant before and after contrast-enhanced. There was remarkable difference between renal cortex and renal tumor in gray-scale value after injection ultrasound agent. Conclusion: Lipid ultrasound contrast agent can effectively enhance the imaging of renal tumors and improve the detection of specificity.

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Kidney neoplasms / Ultrasonography / Doppler / color / Contrast media

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ZENG Gong-jun;LIU Jian-hua;GAO Yun-hua;LIU Zheng;TAN Kai-bin;WU Mei. Experimental study on lipid ultrasound contrast agent in imaging and differentiating renal VX2 carcinoma[J]. Journal of China Clinic Medical Imaging. 2008, 19(6): 412-414