CT and MRI features of ganglioglioma and clinical pathological analysis

HUANG Qing-ling; LIU Wen; CAI Zong-yao; ZHANG Zong-jun; LU Guang-ming

Journal of China Clinic Medical Imaging ›› 2008, Vol. 19 ›› Issue (9) : 623-626.

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CT and MRI features of ganglioglioma and clinical pathological analysis

HUANG Qing-ling1, LIU Wen1, CAI Zong-yao1, ZHANG Zong-jun2, LU Guang-ming2

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Abstract

Objective: To better characterize and report the images of the ganglioglioma(GG) in a series of 17 cases. Methods: Clinical and pathologic features of all cases were retrospectively studied. Results: This group included 17 patients. All cases demonstrated solitary lesion. Fifteen lesions located in supratentorial region, 2 lesions situated in the subtentorial region. Among them, 6 lesions located in the temporal lobe, 5 lesions located in the frontal lobe, 2 lesions located in the parietal lobe, 4 lesions located in the corpus callosum, frontal-temporal lobe, left cerebellum and medulla-cervical cord respectively. CT scan of 3 cases disclosed moderate hypodense lesion, 1 isodense, without peritumoral edema, 1 lesion with bone resorption. On MRI 7 lesions displayed gyriform granulose, 5 lesions were elliptical, the rest were irregular in shape. There were 6 mural nodule in 17 lesions. On T1WI the lesions appeared to be hypointense; T2WI, hyperintense or mixed signal; and absence of contrast enhancement. On T2 fluid attenuated inversion recovery weighted images, the margin and the mural nodule of the lesion appeared to be hyperintense. On DWI the lesions appeared to be isointense to hypointense, while the apparent diffusion coefficient(ADC) value was high. Conclusion: The typical neuroradiologic aspect of GG may be helpful for the diagnosis preoperatively.

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Glioma / Magnetic resonance imaging

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HUANG Qing-ling;LIU Wen;CAI Zong-yao;ZHANG Zong-jun;LU Guang-ming. CT and MRI features of ganglioglioma and clinical pathological analysis[J]. Journal of China Clinic Medical Imaging. 2008, 19(9): 623-626