Clinical implications of transient left ventricular ischemic dilation of coronary artery disease in men

ZHENG Hong-ming; FANG Feng-ning; FENG Jue; WANG Ya-ping

Journal of China Clinic Medical Imaging ›› 2009, Vol. 20 ›› Issue (10) : 755-757.

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Clinical implications of transient left ventricular ischemic dilation of coronary artery disease in men

ZHENG Hong-ming, FANG Feng-ning, FENG Jue, WANG Ya-ping

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Abstract

Objective:　To study the clinical significance of left ventricular transient ischemic dilation(TID) with extensive myocardial ischemic coronary artery disease in men. Methods:　Fifty male patients with extensive myocardial ischemic coronary artery disease from 272 outpatients and inpatients, and 33 without myocardial ischemic coronary artery disease were enrolled into this study with the latter as the control group. SPECT scintigraphy imaging of stress/rest myocardial perfusion were completed after iv. injection of 740MBq 99Tcm-MIBI. The degree of coronary artery disease and ischemia were graded with SSS and SDS. TID was calculated with software in-synchronism.　Results:　TID in male patients with extensive myocardial ischemia and those without ischemia was 1.13±0.13 and 1.01±0.10 respectively(t=4.214, P<0.01). There was a significant difference. Area under the ROC curve was 0.759, the best criterion was 1.02, sensitivity was 78%, specificity was 63.6%. TID>1.18 had maximum LR+(P<0.01, Area=0.5). Conclusion:　The results suggest that TID assessed using the stress/rest sestamibi SPECT is a useful index for separating extensive myocardial ischemia from those without ischemia in men.

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Coronary disease / Radionuclide imaging

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ZHENG Hong-ming;FANG Feng-ning;FENG Jue;WANG Ya-ping. Clinical implications of transient left ventricular ischemic dilation of coronary artery disease in men[J]. Journal of China Clinic Medical Imaging. 2009, 20(10): 755-757