Clinical implications of transient left ventricular ischemic dilation with coronary artery disease in aged people

ZHENG Hong-ming; CHEN Ying-min

Journal of China Clinic Medical Imaging ›› 2009, Vol. 20 ›› Issue (11) : 826-828.

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Clinical implications of transient left ventricular ischemic dilation with coronary artery disease in aged people

ZHENG Hong-ming1, CHEN Ying-min2

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Abstract

Objective:　To study the clinical implications of left ventricular transient ischemic dilation(TID) with extensive myocardial ischemic coronary artery disease in aged people. Methods: Thirty aged patients with extensive myocardial ischemic coronary artery disease from 356 outpatients and inpatients, and 40 without myocardial ischemic coronary artery disease(control group and aged control group) individuals were enrolled in this study. SPECT scintigraphy imaging of stress/rest myocardial perfusion were completed after iv. injection of 740MBq 99Tcm-MIBI. Degree of coronary artery disease and ischemia were graded with SSS and SDS. Record TID calculated with software in-synchronism.　Results: TID in aged patients with extensive myocardial ischemia and those without ischemia was 1.09±0.15, 1.00±0.09 and 0.99±0.08, respectively(t=－2.50, t=－2.89, P<0.01). There was a significant difference. In aged CAD patients, area under the ROC curve was 0.707(aged control group), the best criterion was 1.02, sensitivity was 70%, specificity was 75%; area under the ROC curve was 0.739(younger control group), the best criterion was 1.14, specificity was 100%. Conclusion: The results suggest that TID assessed using the stress/rest sestamibi SPECT is a useful index for separating extensive myocardial ischemia from those without ischemia in aged people.

Key words

Coronary disease / Myocardial ischemia / Technetium tc 99m sestamibi

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ZHENG Hong-ming;CHEN Ying-min. Clinical implications of transient left ventricular ischemic dilation with coronary artery disease in aged people[J]. Journal of China Clinic Medical Imaging. 2009, 20(11): 826-828