Comparative study of SPECT between patients with depressive disorder and anxiety disorders

JIN Yu-xin; GAO De-jiu; LIU Lin

Journal of China Clinic Medical Imaging ›› 2009, Vol. 20 ›› Issue (12) : 0-888.

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Comparative study of SPECT between patients with depressive disorder and anxiety disorders

JIN Yu-xin, GAO De-jiu, LIU Lin

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Abstract

Objective: To study the characteristics of regional cerebral blood flow(rCBF) and the diagnostic value of brain SPECT in patients with depressive disorder and anxiety disorders. Methods: SPECT were performed in 21 depressive patients, 17 anxiety patients to compare the difference in cerebral perfusion. Region of interest(ROI) in cross-sectional images of the brain lobes were drawn, to semi-quantitatively analyse the rCBF changes of depression and anxiety disorders in patients. The t test was used to analyze the quantitative data. Results: Lower radioactivity rate in bilateral prefrontal lobes, temporal lobes, occipital lobes, bilateral parietal lobes, cingulated gyrus, caudate nucleus were demonstrated in the depressive patients(P＜0.05 or 0.01). Lower radioactivity rate in bilateral frontal lobes, anterior temporal lobes and cerebral ganglion were demonstrated in the anxiety patients(P＜0.05 or 0.01). Conclusion: The depressive disorder and anxiety disorders have obvious effect on cerebral blood flow. Radionuclide imaging have important value in the diagnosis and differential diagnosis of depressive disorder and anxiety disorders.

Key words

Depressive disorder / Anxiety disorders / Tomography / emission-computed / single-photon

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JIN Yu-xin;GAO De-jiu;LIU Lin. Comparative study of SPECT between patients with depressive disorder and anxiety disorders[J]. Journal of China Clinic Medical Imaging. 2009, 20(12): 0-888