Evaluation of MSCT application in prognosis and follow-up studies of 60 patients with active pulmonary tuberculosis

WU Jian-lin; LU Xi-wei; ZHANG Jing-wen; ZHANG Qing; ZHANG Guo-qing; LIU Wei

Journal of China Clinic Medical Imaging ›› 2009, Vol. 20 ›› Issue (2) : 84-88.

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Evaluation of MSCT application in prognosis and follow-up studies of 60 patients with active pulmonary tuberculosis

WU Jian-lin1, LU Xi-wei2, ZHANG Jing-wen1, ZHANG Qing1, ZHANG Guo-qing2, LIU Wei2

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Abstract

Objective: To investigate MSCT manifestations after the healing of active pulmonary tuberculosis, and estimate the value of CT in detecting prognosis and follow-up of pulmonary tuberculosis. Material and Methods: Sixty bacteriologically-cured patients with smear-positive pulmonary tuberculosis were included in this study, whose CT manifestations of pre-treatment, post-treatment and 6 months follow-up were observed. CT images were also acquired at the end of expiration. The small airway obstruction and air trapping signs were observed, and explored the correlation between the air trapping volume and pulmonary function parameters. Results: In pre-treatment, post-treatment and 6 months follow-up, the detection rate of activity signs in CT was 95.0%, 31.7% and 1.7%, respectively. The accuracy of CT diagnosing the activity of pulmonary tuberculosis was 95.0%, 68.3% and 96.7% in pre-treatment, post-treatment and 6 months follow-up respectively. The residual lesions were found to be reduced in size and absorbed after drug withdrawal for 6 months in 39 cases(76.5%). Small airway lesions still existed after treatment. The air trapping volume had an obvious correlation with FEF50% and MMEF(χ2=10.48, P<0.01). Conclusions: The CT manifestations of prognosis are demonstrated later than bacteriology. There is a limitation in assessing the activity of pulmonary tuberculosis only by CT signs. CT plays a role in demonstration of secondary small airway changes after bacteriologically cured.

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Tuberculosis / pulmonary / Tomography / sprial computed

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WU Jian-lin;LU Xi-wei;ZHANG Jing-wen;ZHANG Qing;ZHANG Guo-qing;LIU Wei. Evaluation of MSCT application in prognosis and follow-up studies of 60 patients with active pulmonary tuberculosis[J]. Journal of China Clinic Medical Imaging. 2009, 20(2): 84-88