Localization of epileptogenic foci caused by hippocampal sclerosis using MSI

SUN Ji-lin; WU Jie; LI Su-min; LI Lan-ying

Journal of China Clinic Medical Imaging ›› 2009, Vol. 20 ›› Issue (3) : 153-155.

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Localization of epileptogenic foci caused by hippocampal sclerosis using MSI

SUN Ji-lin, WU Jie, LI Su-min, LI Lan-ying

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Abstract

Objective: To evaluate the value of magnetic source imaging(MSI) in localization of the epileptogenic foci in temporal lobe epilepsy(TLE) caused by hippocampal sclerosis(HS). Methods: Sixteen patients with HS were evaluated with magnetoencephalography(MEG) before surgical excision, whose epileptogenic foci were located by MSI. Results: In the follow-up according to Nanjing Military Hospital, 14 patients(87.5%) received satisfying curative effect; 1 patient(6.25%) was partially relieved and 1 patient(6.25%) got poor effect, with a total effective rate of 93%. The concordance of MSI and Video-EEG in localization of epileptogenic foci was 62.5%. Conclusion: MSI could be a new valuable noninvasive functional neuroimaging technique for identification and delineation of epileptogenic foci in presurgical evaluation.

Key words

Epilepsy / temporal lobe / Magnetic resonance imaging / Magnetoencephalography

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SUN Ji-lin;WU Jie;LI Su-min;LI Lan-ying. Localization of epileptogenic foci caused by hippocampal sclerosis using MSI[J]. Journal of China Clinic Medical Imaging. 2009, 20(3): 153-155