MR imaging findings of the tumor-mimicking primary angiitis of the central nervous system

ZHENG Kui-hong; MA Lin; SHI Li-jing; GUO Yong; HUANG Min-hua; ZHANG Yan-qun; ZHAO Shu-chen

Journal of China Clinic Medical Imaging ›› 2010, Vol. 21 ›› Issue (11) : 761-764.

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MR imaging findings of the tumor-mimicking primary angiitis of the central nervous system

ZHENG Kui-hong1, MA Lin2, SHI Li-jing1, GUO Yong1, HUANG Min-hua1, ZHANG Yan-qun1, ZHAO Shu-chen1

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Abstract

Objective: To describe the MRI features of the tumor-mimicking primary angiitis of the central nervous system(PACNS) and to discuss MR diagnostic value of the tumor-mimicking PACNS. Materials and Methods: Eight patients with biopsy-proven PACNS mimicking brain tumor underwent MRI were reviewed. The findings of MR imaging were retrospectively analyzed and the clinical symptoms were also analyzed. Results:　MR imaging demonstrated solitary mass in 6 cases, and multiple mass in 2 cases. On T1WI, the lesions showed homogeneous low signal in 3 cases, and mixed high and low signal in 5 cases. On T2WI, the lesions presented as homogeneous high signal in 3 cases and inhomogeneous high signal in 5 cases. All 8 cases with Gd-DTPA administration, marked enhancement was seen. All lesions of 8 cases showed mass-like enhancement. Conclusion: It is a difficult task to make the correct diagnosis of the tumor-mimicking PACNS, and this disease entity is often misdiagnosed as tumor by MRI. The comprehensive understanding of the MRI characteristic features would be helpful in diagnosing the tumor-mimicking PACNS, thus avoiding the devastating injury caused by surgery. The definite diagnosis relies on brain biopsy.

Key words

Vasculitis / central nervous system / Magnetic resonance imaging / Pathology

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ZHENG Kui-hong;MA Lin;SHI Li-jing;GUO Yong;HUANG Min-hua;ZHANG Yan-qun;ZHAO Shu-chen. MR imaging findings of the tumor-mimicking primary angiitis of the central nervous system[J]. Journal of China Clinic Medical Imaging. 2010, 21(11): 761-764