Diagnostic value of thyroid cold nodules by using 99Tcm-HL91/99Tcm-MIBI imaging

YANG Fan; YUAN Wei-hong; ZHANG Yi; YANG Jian-xian; YUE Jiang-hong; LING Gang-bo

Journal of China Clinic Medical Imaging ›› 2010, Vol. 21 ›› Issue (5) : 316-318.

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Diagnostic value of thyroid cold nodules by using 99Tcm-HL91/99Tcm-MIBI imaging

YANG Fan, YUAN Wei-hong, ZHANG Yi, YANG Jian-xian, YUE Jiang-hong, LING Gang-bo

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Abstract

Objective: To evaluate the diagnostic value of 99Tcm-HL91 and 99Tcm-MIBI imaging in thyroid cold nodules with the qualitative and semi-quantitative analysis. Methods: 103 patients with cold nodules underwent SPECT tumor imaging before operation. Thirty-five patients underwent 99Tcm-HL91 imaging, 68 patients underwent 99Tcm-MIBI imaging; and then comparing the qualitative and semi-quantitative analysis of the early and delayed images in the two groups. Results: The accuracy and specificity of 99Tcm-HL91 hypoxia imaging in the diagnosis of thyroid cold nodules were higher than 99Tcm-MIBI tumor imaging, there was a significant difference(P<0.001); the sensitivity of the two imaging methods had no significant difference. Conclusion: 99Tcm-HL91 imaging in differentiating malignant from benign thyroid cold nodules is more useful than 99Tcm-MIBI imaging.

Key words

Thyroid neoplasms / Radionuclide imaging

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YANG Fan;YUAN Wei-hong;ZHANG Yi;YANG Jian-xian;YUE Jiang-hong;LING Gang-bo. Diagnostic value of thyroid cold nodules by using 99Tcm-HL91/99Tcm-MIBI imaging[J]. Journal of China Clinic Medical Imaging. 2010, 21(5): 316-318