A preliminary study of myocardial contrast echocardiography for coronary microvascular endothelial dysfunction inpatients with angiographical normal coronary arteries

LI Xin; CHEN Yu; HE Sheng; ZHANG Yun-shan; HE Jiang-chun

Journal of China Clinic Medical Imaging ›› 2011, Vol. 22 ›› Issue (11) : 783-785.

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A preliminary study of myocardial contrast echocardiography for coronary microvascular endothelial dysfunction inpatients with angiographical normal coronary arteries

LI Xin, CHEN Yu, HE Sheng, ZHANG Yun-shan, HE Jiang-chun

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Abstract

Objective: To evaluate myocardial contrast echocardiography for the coronary microvascular endothelial dysfunction in patients without showing coronary obstruction by angiography. Methods: Twenty subjects with angiographically normal coronary arteries were involved in group 2. Twenty healthy volunteers without risk factors for coronary artery disease were control group 1. Real-time myocardial contrast echocardiography(MCE) were performed and flash imaging were applied to evaluate myocardial microcirculation perfusion. The peak video intensity(PI), the time to peak concentration(TP) and the duration time(T) were recorded and analyzed in two groups. Results: The PI of group 2 were lower than that in group 1(P<0.05). The TP and the T of group 2 were longer than those in group 1(P<0.05). Conclusions: Coronary microvascular endothelial dysfunction could be detected early in groups with risk factors for coronary artery disease by MCE.

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Coronary disease / Microcirculation / Coronary angiography

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LI Xin;CHEN Yu;HE Sheng;ZHANG Yun-shan;HE Jiang-chun. A preliminary study of myocardial contrast echocardiography for coronary microvascular endothelial dysfunction inpatients with angiographical normal coronary arteries[J]. Journal of China Clinic Medical Imaging. 2011, 22(11): 783-785