Applications of MR whole body DWI in multiple bone tumors

LIU Shuai; ZHAO Wei-dong; CHEN Peng; ZHANG Hong-yu; CAI Lin

Journal of China Clinic Medical Imaging ›› 2011, Vol. 22 ›› Issue (11) : 790-793.

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Applications of MR whole body DWI in multiple bone tumors

LIU Shuai1, ZHAO Wei-dong1, CHEN Peng2, ZHANG Hong-yu1, CAI Lin1

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Abstract

Objective: To investigate the value of whole body DWI(WB-DWI) in differential diagnosis of multiple bone metastases and multiple myeloma. Materials and Methods: Fifty-seven cases with multiple bone tumors and 12 cases normal volunteers underwent WB-DWI. Furthermore, the signal characteristic and ADC values of the thoracic, lumbar vertebrae, and llilac bone were analyzed and measured respectively. In addition, the detection frequency for searching primary tumors in patients with multiple osseous metastases was calculated. Results: Multiple osseous tumors demonstrate abnormal high signals on WB-DWI. The ADC value of multiple osseous metastases were higher than that of multiple myeloma. Meanwhile, the ADC value of multiple myeloma and multiple osseous metastases were markedly higher than that of normal bone. The difference was significant in ADC values between multiple myeloma and multiple osseous metastases(P<0.01). The detection frequency for searching primary tumors in patients with multiple osseous metastases was 74.5%(35/47). Conclusion: Multiple osseous metastases and multiple myeloma can be differentiated by quantitative analysis with ADC value. The WB-DWI can demonstrate primary tumors, which also can help to differentiate multiple osseous metastases and multiple myeloma.

Key words

Bone neoplasms / Neoplasm metastasis / Diffusion magnetic resonance imaging

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LIU Shuai;ZHAO Wei-dong;CHEN Peng;ZHANG Hong-yu;CAI Lin. Applications of MR whole body DWI in multiple bone tumors[J]. Journal of China Clinic Medical Imaging. 2011, 22(11): 790-793