Abstract
Objective: To discuss the correlation of pathology, CT features and serum CEA concentration in peripheral lung cancer. Materials and Methods: The pathology, CT features and the serum CEA concentration in 48 cases of peripheral lung cancer, confirmed by operation and pathology, were analyzed. Results: The serum CEA concentration was (13.23±20.47)ng/ml(adenocarcinoma, n=30), (3.62±2.48)ng/ml(squamous carcinoma, n=11). There was no correlation between the serum CEA concentration and the tumor differentiation degree in lung cancer(r=-0.017). The serum CEA concentration were higher in lung cancer with deep lobulation sign or diameter≥3cm. There was no significant difference between lung cancer with pleural indentation sign, spiculation sign, increased CT value≥20HU after enhancement, calcification or enlargement of hilar or mediastinal lymph nodes and serum CEA concentration. There was positive correlation between the percentage of Ki-67 antigen and the serum CEA concentration in lung cancer(r=0.576). The serum CEA concentration was (19.37±24.40)ng/ml(p53 positive group), (3.64±2.11)ng/ml(p53 negative group). Conclusion: There was positive correlation between serum CEA concentration, the percentage of Ki-67 antigen, expression of p53, deep lobulation sign and diameter≥3cm of peripheral lung cancer. There was no significant difference between tumor differentiation degree and serum CEA concentration in peripheral lung cancer.
Key words
Lung neoplasms /
Carcinoembryonic antigen /
Tomography /
spiral computed
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TAN Li-lian;ZHOU Jie;LI Zhi-ming;JIANG Jin-dai;LI Shu-xin;ZHANG Wan-hong.
Correlation study of CT features, pathology and the serum CEA concentration in peripheral lung cancer[J]. Journal of China Clinic Medical Imaging. 2011, 22(7): 464-467
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