Ultrasonic elastography and 18F-FDG PET/CT in differential diagnosis of thyroid nodules

AN Xiu-yan; CONG Shu-zhen; QIAN Jun; GUO Yu-ping; WANG Min

Journal of China Clinic Medical Imaging ›› 2012, Vol. 23 ›› Issue (10) : 692-694.

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Ultrasonic elastography and 18F-FDG PET/CT in differential diagnosis of thyroid nodules

AN Xiu-yan, CONG Shu-zhen, QIAN Jun, GUO Yu-ping, WANG Min

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Abstract

Objective: To compare the value of ultrasonic elastography(UE) with 18F-FDG PET/CT in differentiating benign and malignant thyroid nodules. Methods: Eighty-nine patients with 115 lesions in the thyroid were retrospective studied. All the patients underwent UE and 18F-FDG PET/CT. Pathologic outcome was used as the gold diagnosis criterion. The sensitivity, specificity, accuracy of UE in diagnosing thyroid nodules were compared with 18F-FDG PET/CT. Results: Sensitivity, specificity and accuracy of UE were 87.06%, 93.05% and 72.4%, and that of 18F-FDG PET/CT were 96.55%, 66.28% and 73.91%. The accuracy of UE was higher than 18F-FDG PET/CT in differentiating benign and malignant thyroid nodules(χ2=14.29, P<0.05). Conclusion: UE has better diagnostic value than 18F-FDG PET/CT in differentiating benign and malignant thyroid nodules.

Key words

Thyroid nodule / Ultrasonography / Doppler / color / Positron-emission tomography / Tomography / X-ray computed

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AN Xiu-yan;CONG Shu-zhen;QIAN Jun;GUO Yu-ping;WANG Min. Ultrasonic elastography and 18F-FDG PET/CT in differential diagnosis of thyroid nodules[J]. Journal of China Clinic Medical Imaging. 2012, 23(10): 692-694