The role of 18F-FDG PET-CT in the detection of primary lesions for patients with tumor metastasis

GE Ran; ZHAO Li-xia; TIAN Rong; SU Ming-gang; LI Lin

Journal of China Clinic Medical Imaging ›› 2012, Vol. 23 ›› Issue (10) : 722-726.

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The role of 18F-FDG PET-CT in the detection of primary lesions for patients with tumor metastasis

GE Ran1, ZHAO Li-xia2, TIAN Rong1, SU Ming-gang1, LI Lin1

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Abstract

Objective: To evaluate the 18F-FDG PET-CT in detecting primary foci in cases of suspected metastatic tumor. Methods: One hundred and sixty-four patients with pathologically proved metastasis of unknown primary tumor underwent 18F-FDG PET-CT scan. Statistical analysis was performed after the final follow up. Result: The total positive rate, specificity, sensitivity, accuracy, negative predictive value and positive predictive value were 51.2%(84/164), 97.3%(71/73), 92.3%(84/91), 94.5%(155/164), 91.0%(71/78), 97.7%(84/86) respectively. The positive rate of the primary foci for metastatic adenocarcinoma, metastatic squamous carcinoma and metastatic undifferentiated carcinoma were 54.0%(47/87), 56.8%(21/37) and 40.0%(12/30) respectively. According to the statistical analysis, there was no statistical difference among the positive rate of the three groups. Conclusion: 18F-FDG PET-CT might be of importance in the detection of primary site in unknown primary tumors

Key words

Neoplasms / unknown primary / Fluorodeoxyglucose F18 / Positron-emission tomography / Tomography / spiral computed

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GE Ran;ZHAO Li-xia;TIAN Rong;SU Ming-gang;LI Lin. The role of 18F-FDG PET-CT in the detection of primary lesions for patients with tumor metastasis[J]. Journal of China Clinic Medical Imaging. 2012, 23(10): 722-726