Objective: To evaluate the changes of cerebral perfusion and hemodynamics in the patients with carotid cavernous fistula(CCF) after transcatheter embolization with the technique of DSA parametric imaging. Methods: The images were processed by Photoshop and Screenshot software in personal computer. The following parameters of the ROIs in the internal carotid artery, brain tissue, superior sagittal sinus were acquired, respectively. These parameters includes: the peak value(PV) of brain pre- and post-embolization, and the parameters including time of appearance(TA), relative mean transit time(RMTT), time to peak(TP) and relative time of cerebral circulation(RTCC) were also evaluated, respectively. The results were statistically evaluated by matched-t test. Results: ①Before the operation, the values of PV, TP, TA, RMTT, RTCC of the brain were 40.75±2.99, (1.85±0.39) s, (0.48±0.36) s, (2.00±0.80) s, (1.30±0.55) s, respectively; after the operation, the values of the above-mentioned parameters were 56.50±5.69, (2.95±0.13) s, (0.85±0.31) s, (2.88±0.74) s, (3.23±0.67) s, respectively; the difference of the parameters pre- and post-operation were statistically significant(t=9.26, 8.12, 5.00, 5.30 and 9.97; P<0.05)． ②Before the operation, the values of PV, TP in the internal carotid artery were 77.00±10.68, (0.88±0.22) s, respectively; after the operation, the values of PV, TP in the internal carotid artery were 98.00±3.67, (1.38±0.10) s, respectively; the difference of the parameters pre- and post-operation were statistically significant(t=4.60, 3.69; P<0.05)． Before the operation, the values of TA, RMTT in the internal carotid artery were (0.26±0.19) s, (1.45±0.40) s, respectively; after the operation, the values of TA, RMTT in the internal carotid artery were (0.36±0.21) s, (2.08±0.60) s, respectively; there were no statistical significance(t=2.45, 1.33; P>0．05)． Conclusion: DSA parametric imaging can be used to evaluate the changes of cerebral perfusion and hemodynamics in CCF before and after transcatheter embolization.
Key words
Carotid-cavernous sinus fistula /
Angiography /
digital subtraction
