Abstract
Objective: To investigate the parameters obtained with 320 CT perfusion imaging in cervical cancer and the clinical application. Methods: Thirty-six cases of cervical cancer patients were scanned with Aquilion ONE 320 CT, including 16 cases of stage Ⅰ~Ⅱ cervical cancer and 20 cases of stage Ⅲ~Ⅳ cervical cancer. Fifteen cases of parametrial normal tissues were considered as a control group. Time-density curves(TDC), as well as perfusion parameters, including blood flow(BF), blood volume(BV) and permeability surface(PS) were post-processed by perfusion CT software package. Results: BF, BV and PS were higher in the stage Ⅰ~Ⅱ and Ⅲ~Ⅳ cervical cancer groups than those in the parametrial normal control group; BF, BV and PS were higher in the stage Ⅲ~Ⅳ group than those in the Ⅰ~Ⅱ stage cervical cancer group, with statistically significant differences(P<0.05). Perfusion parameters enhanced with the increase of the tumor stage. Conclusions: 320 CT perfusion imaging in cervical cancer provides a new method to reliably demonstrate the parameters of perfusion imaging and internal perfusion, thus, it is clinically significant for tumor staging, prognosis and evaluation of tumor therapy.
Key words
Cervix neoplasms /
Tomography /
spiral computed
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QIAN Hao-chu;GUO Wen-li;WANG Si-liang;HU Tian-yu;WU Rong.
A study of CT perfusion imaging of cervical cancer on Aquilion ONE 320[J]. Journal of China Clinic Medical Imaging. 2012, 23(12): 853-855
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