Diagnostic value of contrast enhanced US for cystic renal masses: a Meta analysis

WU Lei; ZHA Yun-fei; CHEN Wen; GONG Xiao-hong

Journal of China Clinic Medical Imaging ›› 2013, Vol. 24 ›› Issue (11) : 780-783.

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Diagnostic value of contrast enhanced US for cystic renal masses: a Meta analysis

WU Lei1, ZHA Yun-fei2, CHEN Wen1, GONG Xiao-hong1

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Abstract

Objective: To assess the diagnostic value of contrast enhanced ultrasound technology in the diagnosis of cystic renal masses by Meta-analysis. Methods: Contrast enhanced ultrasound and cystic renal masses were selected as the keywords. Searching the Cochrane library, PubMed, Embase, CNKI and the WANFANG DATA, the original data were abstracted and performed heterogeneity test with the Meta-Disc software. The weighted sensitivity, specificity, positive likelihood ratio and negative likelihood ratio were calculated, as well as the summary receiver operating characteristic(SROC) curve. Further estimated the diagnostic value of contrast enhanced ultrasound in the research of cystic renal masses by calculating the area under the curve. The quality of evidence in researches were evaluated by QUADAS items. Result: A total of 7 studies including four Chinese papers and three English articles were adopted for Meta-analysis. According to the random effects model, the weighted sensitivity, specificity, positive likelihood ratio, negative likelihood ratio，diagnostic odds ratio were 0.92, 0.84, 4.54, 0.09, 69.9, respectively; and the area under the curve was 0.952. Conclusion: Contrast enhanced ultrasound technology has a good diagnostic and clinical value in the study of cystic renal masses.

Key words

Kidney neoplasms / Kidney / cystic / Ultrasonography / Meta-analysis

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WU Lei;ZHA Yun-fei;CHEN Wen;GONG Xiao-hong. Diagnostic value of contrast enhanced US for cystic renal masses: a Meta analysis[J]. Journal of China Clinic Medical Imaging. 2013, 24(11): 780-783