The reliability of 3D TOF MRA for preoperative assessment of intracranial vascular stenosis by 3.0T MR system

SUN Jing; ZHANG Shi-de; WEI Yong-bing; BAI Lin-gang

Journal of China Clinic Medical Imaging ›› 2013, Vol. 24 ›› Issue (3) : 153-158.

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The reliability of 3D TOF MRA for preoperative assessment of intracranial vascular stenosis by 3.0T MR system

SUN Jing1, ZHANG Shi-de2, WEI Yong-bing1, BAI Lin-gang3

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Abstract

Objective: To explore the reliability of 3D TOF MRA on 3.0T MR system for preoperative assessment of intracranial vascular stenosis. Methods: Thirty patients with intracranial arterial stenosis in the 2nd Hospital Affiliated to Harbin Medical University, who received both 3D TOF MRA on a 3.0T MR system and rotational digital subtraction angiography examinations. 450 vascular segments of the 30 patients were analysed. Without stenosis, mild stenosis(10%~＜50%), stenosis of 50%, 70%, 100% as decision point to calculate sensitivity, specificity, positive predictive value(PPV) and negative predictive value(NPV) of MRA. Results: Compared to DSA, 115 lesions were detected, the sensitivity and specificity were 87.0% and 99.7% for MRA in detecting stenosis. Take 50% as the critical point. The sensitivity and specificity was 86.7% and 99.5% respectively, the PPV was 92.9% and the NPV was 99.1%. Take 70% as the critical point the sensitivity and specificity was 95.5%, 99.5% respectively, PPV 91.3% and NPV 99.5%. MRA diagnosed 7 in the eight occlusions. One false positive and one false negative(that was stenosis of the basilar artery and intracranial segment of the vertebral artery). Twenty-eight(24.6%) segments were overestimated, 7 segments were underestimated. Conclusion: To determine 50% and 70% intracranial arterial stenosis, 3.0T 3D TOF MRA has high sensitivity and specificity compared to rotational DSA, and can be used as an effective means in pre-stenting surgery.

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Arteriosclerosis / Angiography / digital subtraction / Magnetic resonance angiography

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SUN Jing;ZHANG Shi-de;WEI Yong-bing;BAI Lin-gang. The reliability of 3D TOF MRA for preoperative assessment of intracranial vascular stenosis by 3.0T MR system[J]. Journal of China Clinic Medical Imaging. 2013, 24(3): 153-158