Initial study of functional MRI on self-focused attention in depression patients

DONG Hai-bo; MA Xiao-jie; CHEN Chuan-feng; LI Ya-di

Journal of China Clinic Medical Imaging ›› 2013, Vol. 24 ›› Issue (6) : 381-384.

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Initial study of functional MRI on self-focused attention in depression patients

DONG Hai-bo1, MA Xiao-jie2, CHEN Chuan-feng2, LI Ya-di1

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Abstract

Objective: To explore the cerebral activation of depression patients when performing self-focused attention tasks and the correlation between self-focused attention and depression. Methods: Eight depressive patients and nine healthy volunteers underwent fMRI scan using three self-focused attentional patterns stimulus in a block design, SPM8 software was used for image data processing. Comparative brain activation maps between depression patients and healthy volunteers were carried out. Results: The active areas of depressive patients are more extensive than that of healthy volunteers in three target stimulus conditions. For the depressed patients, the active areas in the “I” target stimulus conditions are more extensive than that of “He” and “*” conditions. Conclusion: Depressive patients may have self-focused attentional bias, self-focused attention might be associated with depression.

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Depressive disorder / Magnetic resonance imaging

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DONG Hai-bo;MA Xiao-jie;CHEN Chuan-feng;LI Ya-di. Initial study of functional MRI on self-focused attention in depression patients[J]. Journal of China Clinic Medical Imaging. 2013, 24(6): 381-384