Imaging findings of abdominal endodermal sinus tumor in children

WU Hui-ying; XU Wen-biao; TIAN Jin-sheng; AI Bin; LI Jian-ming

Journal of China Clinic Medical Imaging ›› 2015, Vol. 26 ›› Issue (2) : 99-104.

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Imaging findings of abdominal endodermal sinus tumor in children

WU Hui-ying, XU Wen-biao, TIAN Jin-sheng, AI Bin, LI Jian-ming

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Abstract

Objective: To evaluate imaging findings of abdominal endodermal sinus tumor(EST) in children. Methods: Thirty-six cases of pelvic and abdominal EST were retrospectively reviewed from 2008 to 2013. Clinical data and CT findings were analyzed. All cases were confirmed by operation and pathology. Results: Mean age of the patients was 2 years and 3 months(ranging from 5 months to 10 years old) and 30 patients were less than 3 years old. 27 females and 9 males were included. The tumors were located in gonads in 4 cases(3 cases in the ovary and 1 case in the cryptorchidism), and out of the gonads in 32 cases, especially in sacrococcygeal region(17 cases) and pelvic and abdominal cavity(10 cases). 12 cases had metastasis, including 6 cases of lymphatic metastases and 12 cases of infiltration and hematogenous metastases. 6 patients relapsed within 2 years. CT manifestations: mean size of the tumors was 6 cm(1～10 cm). 25 tumor were greater than 5 cm. 20 tumors showed morphologically irregular and 16 were regular. 31 cases revealed solid mass on plain CT scan and 5 cases revealed cyst-solidary mass. All tumors showed some tiny vessels and irregular reticular enhancement in post-contrast CT scan. Later, they showed nodular and flocculent enhancing around the tumor. Conclusion: EST in abdomen is a highly malignant germ cell tumor in children. CT findings have some features and have important value in diagnosis.

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Endodermal sinus tumor / Abdominal neoplasms / Tomography / spiral computed

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WU Hui-ying;XU Wen-biao;TIAN Jin-sheng;AI Bin;LI Jian-ming. Imaging findings of abdominal endodermal sinus tumor in children[J]. Journal of China Clinic Medical Imaging. 2015, 26(2): 99-104