Abstract
Objective: A Meta-analysis was performed to investigate the diagnostic value of Magnetic Resonance Elastography(MRE) for different stages of hepatic fibrosis. Methods: English articles related to MRE diagnosis for hepatic fibrosis from various data resources including PUBMED, EMBASE, Web of Science, and Cochrane Library database were collected and evaluated. Using a checklist based on the Quality Assessment for Studies of Diagnostic Accuracy-2(QUADAS-2), the methodological quality of each study was characterized. Stata 12.0 software was used to synthetically analyze the experimental data from different English literatures. Results: 18 studies were finally collected which met all inclusion criteia. The pooled sensitivity and specificity for F≥1, F≥2, F≥3, and F=4 were 0.87, 0.9, 0.94, 0.98 and 0.95, 0.94, 0.91, 0.94, and the areas under curve(AUC) were 0.97, 0.97, 0.96, and 0.98, respectively. Conclusion: MRE has a higher diagnostic value for determining different hepatic fibrosis stages.
Key words
Liver cirrhosis /
Magnetic resonance imaging /
Meta-analysis
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WANG Wei;WEN Feng;ZHAO Xiang-xuan;SHI Yu;WANG Yue-ren;GUO Qi-yong.
A Meta-analysis of magnetic resonance elastography for the staging of hepatic fibrosis[J]. Journal of China Clinic Medical Imaging. 2015, 26(5): 329-333
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