Amplitude low-frequency oscillation abnormalities in trigeminal neuralgia patients

YAN Jian-hao; WANG Tian-yue; LI Meng; LI Chao; XIA Li-kun; YIN Yi; ZHAN Wen-feng; JIANG Gui-hua

Journal of China Clinic Medical Imaging ›› 2017, Vol. 28 ›› Issue (5) : 318-320.

YAN Jian-hao, WANG Tian-yue, LI Meng, LI Chao, XIA Li-kun, YIN Yi, ZHAN Wen-feng, JIANG Gui-hua

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Abstract

Abstract: Objective: To explore the regional spontaneous activity changes in the whole brain of trigeminal neuralgia(TN) patients using resting-state fMRI. Methods: Resting-state fMRI datasets of 30 TN patients and 20 healthy controls were acquired. The amplitude low-frequency fluctuation(ALFF) and independent-sample t-test were used to compare the brain activity abnormalities between these two groups. Results: In TN patients, we found decreased ALFF in the left superior temporal gyrus and left fusiform, as well as an increased ALFF in the left frontal med orb and left sup motor area. Conclusion: Our results demonstrated the spontaneous activity change underlying TNP, and these abnormalities may contribute to the cognization and emotion of the pain.

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Trigeminal neuralgia / Magnetic resonance imaging

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YAN Jian-hao, WANG Tian-yue, LI Meng, LI Chao, XIA Li-kun, YIN Yi, ZHAN Wen-feng, JIANG Gui-hua. Amplitude low-frequency oscillation abnormalities in trigeminal neuralgia patients[J]. Journal of China Clinic Medical Imaging. 2017, 28(5): 318-320

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