Shear-wave elastography for the evaluation of residual breast cancer after neoadjuvant chemotherapy

MA Yu-feng; ZHANG Xin; ZHANG Wei; LIU Hong-Shu

Journal of China Clinic Medical Imaging ›› 2018, Vol. 29 ›› Issue (5) : 316-319.

MA Yu-feng, ZHANG Xin, ZHANG Wei, LIU Hong-Shu

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Abstract

Objective: To elucidate the evaluation of shear-wave elastography(SWE) in the residual breast cancer after neoadjuvant chemotherapy(NAC). Methods: 66 breast cancer patients receiving NAC were consecutively included. The means and maximum stiffness after NAC treatment were assessed by SWE. Correlations between the stiffness and pathological response quantized by residual cancer burden(RCB) were determined. Pathological complete response(pCR) was recorded and considered as gold standard. Diagnostic tests of the stiffness value evaluated by SWE were performed. Results: Correlations between the stiffness and pathological response were significantly positive. The maximum stiffness had significantly better overall diagnostic performance than mean stiffness regarding evaluating pCR, and the difference of diagnostic performance between maximum and mean stiffness was significant(P<0.01). Conclusion: The performance of maximum stiffness for evaluating the residual lesion of breast cancer after NAC is favorable, SWE may facilitate the personalizing treatment of breast cancer.

Key words

Breast neoplasms / Antineoplastic combined chemotherapy protocols / Ultrasonography, Doppler, color

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MA Yu-feng, ZHANG Xin, ZHANG Wei, LIU Hong-Shu. Shear-wave elastography for the evaluation of residual breast cancer after neoadjuvant chemotherapy[J]. Journal of China Clinic Medical Imaging. 2018, 29(5): 316-319

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