目的：应用斑点追踪技术测量右室圆周应变。方法：研究对象为肺动脉高压（PAH）患者及健康人。在心尖四腔切面计算右室面积变化率;采集右室短轴二维图像并输入QLAB9.0工作站获取右室圆周应变（ε）。分析两组间差异。结果：右室短轴圆周应变在PAH组和对照组有良好的一致性，均有90%的测值落在应变值差值的95%置信区间；与对照组相比，PAH组右室基底段前壁、游离壁、下壁、中间段游离壁、心尖段前壁及三个切面整体圆周应变降低（P<0.05），且与右室面积变化率有中度的相关性。结论：斑点追踪技术可以测量右室圆周应变，重复性良好，与右室面积变化率具有相关性，PAH患者右室短轴方向收缩功能减低。
Abstract
Objective: To explore right ventricular circumferential strain in pulmonary arterial hypertension(PAH) using speckle tracking echocardiography. Methods: The subjects are PAH patients and healthy controls. Right ventricular fractional area change(RVFAC) was calculated in the apical four-chamber view. Right ventricular short-axis two-dimensional images were aquired. Right ventricular circumferential strain(ε) was collected in the QLAB9.0 workstation. The difference of ε between the two groups was analyzed. Results: Compared with the control group, PAH patients showed decreased circumferential strain in anterior wall, free wall, inferior wall of right ventricle in the basal level, free wall of right ventricle in the middle level, and anterior wall of right ventricle in the apical level. Also, the global circumferential strain of right ventricle was reduced(P<0.05). Right ventricular circumferential strain showed a modest correlation with RVFAC. Conclusion: Right ventricular circumferential strain is decreased in PAH patients, demonstrating that right ventricular short axis contractility of PAH patients is reduced. There is modest correlation between right ventricular circumferential strain and RVFAC.
关键词
高血压 /
肺性；心室功能 /
右；超声心动描记术 /
多普勒 /
彩色
Key words
Hypertension, pulmonary /
Ventricular function, right /
Echocardiography, Doppler, color
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参考文献
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