摘要
目的:总结原发性脑内淋巴瘤的影像表现,探讨伽玛刀的治疗作用。方法:1999年9月~2005年9月,18例(24个病灶)经病理证实的原发性脑内淋巴瘤患者接受伽玛刀治疗,以40%~50%等剂量曲线包绕肿瘤,边缘剂量为13~23Gy,平均16Gy。随访期为6~30个月,平均18个月。结果:伽玛刀治疗后l~2个月肿瘤消失或缩小,临床症状迅速改善,近期有效率为100%。结论:伽玛刀治疗原发性脑内淋巴瘤是一种安全、有效的方法,病灶局部控制率高,它可以缓解神经症状,提高生存质量。
Abstract
Objective: To review CT and MRI feature of primary intracerebral malignant lymphoma(PICML) and to assess the role of the gamma knife radiosurgery in the treatment of PICML. Methods: Eighteen patients with pathology proven PICML were treated with gamma knife radiosurgery from September 1999 to September 2005. They were treated at 40%~50% isodose curve and the tumor margin dose is 13~23Gy. The average margin dose was 16Gy. Eighteen patients with 24 leisons were followed up for 6~30 months with mean 18 months. Results: All lesions treated with gamma knife radiosurgery diminished in size or disappeared within one or two months after treatment, and the neurological deficits had improved dramatically. The local control rate is 100% in the near future. Conclusion: Gamma knife is a safe and effective treatment for PICML, it can relieve neurological symptoms, has a higher local control rate and improves the quality of life.
关键词
淋巴瘤 /
磁共振成像
Key words
lymphoma /
magnetic resonance imaging
姜新雅;仇 斌;陈长青;廖伟华;王小宜.
原发性脑内淋巴瘤伽玛刀治疗前与治疗后的影像学评价[J]. 中国临床医学影像杂志. 2006, 17(10): 541-543
JIANG Xin-ya;QIU Bin;CHEN Chang-qing;LIAO Wei-hua;WANG Xiao-yi.
Imaging study of primary intracerebral malignant lymphoma pre- and post-gamma knife radiosurgery[J]. Journal of China Clinic Medical Imaging. 2006, 17(10): 541-543
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