摘要
目的:探讨磁化传递成像(MTI)在鉴别脑脓肿与坏死囊变性胶质瘤和脑转移瘤的应用价值。材料与方法:7例经手术病理(3例)或临床随访(4例)证实的脑脓肿、9例经手术病理证实的坏死囊变性胶质瘤和8例经临床证实的坏死囊变性转移瘤在治疗前接受了常规MRI、SE序列MTI(SE-MTI)检查,测量并计算病灶囊性区、实性区、同层面对侧正常脑白质区和脑脊液的平均磁化传递率(MTR)。结果:病灶囊性区、实性区、同层面对侧正常脑白质区和脑脊液的MTR分别为0.0770±0.03、0.2239±0.03、0.3089±0.020、-0.0032±0.03;病灶囊性区与脑脊液的MTR之间存在显著性差异,t=9.933,P<0.001,病灶实性区与正常脑白质区的MTR之间存在显著性差异,t=-14.509,P<0.001;脑脓肿与坏死囊变性胶质瘤和脑转移瘤囊性区的MTR存在显著性差异,χ2=17.486,P<0.001,其中脑脓肿与胶质瘤以及脑脓肿与脑转移瘤有显著性差异,P值均<0.001,胶质瘤和脑转移瘤无明显差异,P>0.20;实性区域的MTR三者之间无差异。结论:SE-MTI以及MTR的测量在鉴别脑脓肿与坏死囊变性胶质瘤和脑转移瘤有重要价值,可作为常规MRI序列的重要补充。
Abstract
Objective: To study the value of magnetization transfer imaging(MTI) in the differentiation of brain abscess from necrotic or cystic glioma and metastasis. Materials and Methods: The conventional MR imaging and MTI of SE sequence were performed before operation or treatment in 7 patients with brain abscess(3 cases histopathology verified and 4 cases clinical follow-up confirmed) and 9 patients with necrotic or cystic glioma(confirmed by histopathology) and 8 patients with necrotic or cystic metastasis (clinically confirmed). Mean MTR of cystic and solid parts in abscess, glioma and metastasis, contralateral normal white matters and cerebrospinal fluid were measured and calculated. Results: MTR of cystic and solid parts in all lesions, contralateral normal white matter and cerebrospinal fluid were 0.0770±0.03, 0.2239±0.03, 0.3089±0.020, -0.0032±0.03 respectively. The difference of MTR between cystic parts of all lesions and cerebrospinal fluid was significant(t=9.933, P<0.001). The difference of MTR between solid parts of all lesions and contralateral normal white matters was significant(t=-14.509, P<0.001). The difference of MTRs among abscess, necrotic or cystic area of glioma and metastasis was significant(χ2=17.486, P<0.001), especially, there was significant difference between abscess and necrotic or cystic area of glioma or metastasis(abscess&glioma: P<0.001 and abscess&metastasis: P<0.001), however, there was no difference between necrotic or cystic area of glioma and metastasis(P>0.20). The difference of MTR among solid parts of abscess, glioma and metastasis was not significant. Conclusion: MT imaging and MTR could play an important role in differentiating brain abscess from necrotic or cystic glioma and metastasis on the middle feild, and MR system was an important supplement for routine MRI.
关键词
脑脓肿 /
脑肿瘤 /
磁共振成像
Key words
brain abscess /
brain neoplasms /
magnetic resonance imaging
姚秀忠;陈世勇;赖清泉;粘朝晖;吴 宏;卢文乾.
磁化传递成像在鉴别脑脓肿与坏死囊变性脑肿瘤的应用研究[J]. 中国临床医学影像杂志. 2006, 17(10): 544-546
YAO Xiu-zhong;CHEN Shi-yong;LAI Qing-quan;NIAN Chao-hui;WU Hong;LU Wen-qian.
An application study of magnetization transfer imaging in differentiating brain abscess from necrotic or cystic neoplasm[J]. Journal of China Clinic Medical Imaging. 2006, 17(10): 544-546
中图分类号：
R739.41
R742
R445.2
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