SARS康复者肺部CT表现及肺功能恢复与临床的联系

蓝日辉; 曾庆思; 孙翀鹏; 陈苓; 郑则广; 郑劲平; 吴华

中国临床医学影像杂志 ›› 2006, Vol. 17 ›› Issue (11) : 608-612.

论著

SARS康复者肺部CT表现及肺功能恢复与临床的联系

蓝日辉1，曾庆思1，孙翀鹏1，陈苓1，郑则广2，郑劲平2，吴华2

作者信息 +

The correlation between high resolution CT findings and recovery of respiratory function tests in SARS patients in the convalescent phase

LAN Ri-hui1, ZENG Qing-si1, SUN Chong-peng1, CHEN Ling1, ZHENG Ze-guang2, ZHENG Jin-ping2, WU Hua2

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文章历史 +

摘要

目的：探讨严重急性呼吸综合征（SARS）康复者的肺部CT表现及肺功能恢复情况与临床的联系。方法：49例SARS康复者出院后30～122天进行肺部螺旋CT和/或高分辨CT复查，同期40例进行了肺功能复查，分别有16例和13例康复者出院后120～245天再次进行CT复查和肺功能复查。对康复者的临床资料进行回顾性分析，用CT视觉评分方法定量分析肺内病变。结果：首次49例复查的肺部CT表现为磨玻璃阴影25例（51.0％），间质阴影22例（44.9％），随后16例复查的情况分别为6例（37.5％）和7例（43.8％）。CT视觉评分比较两次CT复查的征象，磨玻璃影有明显吸收，但间质阴影吸收缓慢。住院期间合并成人呼吸窘迫综合征（ARDS）者其磨玻璃阴影评分明显比没有合并ARDS者高。肺弥散功能占预计值的百分比（Dlco％）的恢复与性别和肺部磨玻璃阴影评分有关。结论：SARS康复者肺部CT表现与临床、实验室检查和肺功能密切相关，随时间的延长，肺内病灶及肺功能逐渐好转，但间质阴影吸收缓慢。

Abstract

Objective: To study the correlation between high resolution CT(HRCT) findings, recovery of respiratory function tests and clinical data of SARS patients in the convalescent phase. Methods: Forty-nine patients with confirmed SARS underwent initial thin-section CT and forty patients underwent respiratory function tests. Sixteen and thirteen patients underwent follow-up examination. The clinical data were retrospectively analysed. CT visual score were quantitatively analyzed for lung abnormalities. Results: Ground-glass opacities and interstitial opacities were found in 25(51%), 22(45%) of the 49 patients on initial HRCT and in 6(38%), 7(44%) of the 16 patients on the follow-up HRCT examinations. The initial and follow-up CT visual score indicated a significant reduction in the extent of ground-glass opacity(P<0.001) but not in that of interstitial opacity. Scan from patients with adult respiratory distress syndrome(ARDS) had a significantly higher score for ground-glass opacity than did those from patients without ARDS(P<0.05). Dlco％ were correlated with sex and ground-glass opacity score. Conclusion: HRCT findings were correlated with clinical data, laboratory tests and respiratory function tests, residual abnormalities and respiratory function tend to be better over the time, but interstitial opacity persists.

导出引用

蓝日辉;曾庆思;孙翀鹏;陈苓;郑则广;郑劲平;吴华. SARS康复者肺部CT表现及肺功能恢复与临床的联系[J]. 中国临床医学影像杂志. 2006, 17(11): 608-612

LAN Ri-hui;ZENG Qing-si;SUN Chong-peng;CHEN Ling;ZHENG Ze-guang;ZHENG Jin-ping;WU Hua. The correlation between high resolution CT findings and recovery of respiratory function tests in SARS patients in the convalescent phase[J]. Journal of China Clinic Medical Imaging. 2006, 17(11): 608-612

中图分类号： Ｒ563 Ｒ814.42