摘要
目的:评价99mTc-MIBI双时相显像在甲状旁腺功能亢进症(甲旁亢)诊断中的临床价值。方法:44例拟诊甲旁亢患者进行了99mTc-MIBI双时相显像。阳性指标为延迟图像上出现异常增高的放射性聚集,显像资料均参照临床最终诊断结果进行评价,并与同期的B超或CT检查作了对比分析。结果:44例患者中,33例确诊为甲旁亢,其中甲状旁腺腺瘤31例(包括异位1例)、甲状旁腺增生1例与甲状旁腺癌1例。诊断灵敏度为90.9%,特异度为100%,准确性为93.2%,同期B超诊断灵敏度和准确性为70%与77.3%。另25例患者有CT资料,12例有阳性发现(60%)。99mTc-MIBI双时相显像在甲旁亢的诊断中具有较高的阳性率,在腺瘤诊断方面较B超和CT具有更高的诊断效能(P<0.05)。结论:99mTc-MIBI双时相显像能较准确的检测功能亢进的甲状旁腺,是患者术前定位的重要辅助诊断手段,值得临床推广应用。
Abstract
Objective: To evaluate the clinical value of double phase 99mTc-MIBI imaging in diagnosing hyperparathyroidism. Methods: Forty-four patients with highly suspected hyperparathyroidism underwent double phase 99mTc-MIBI imaging. Abnormal increase radioactivity in delay imaging stood for positive index. Imaging material were evaluated according to final clinical results and compared with ultrasound or CT. Results: In 44 patients, 33 hyperparathyroidism were proven, including 31 adenomas(ectopic 1), 1 hyperplasia and 1 carcinoma. The sensitivity and specificity of diagnosis were 90.9%, 100%, respectively. The accuracy of double phase 99mTc-MIBI imaging was 93.2%. The sensitivity and specificity of ultrasound were 70%, 77.3%, respectively. The sensitivity of CT was 60%. The results showed that double phase 99mTc-MIBI imaging was superior to ultrasound and CT(P<0.05). Conclusion: Double phase 99mTc-MIBI imaging could accurately diagnose hyperparathyroidism. It is an important localizing method for preoperation which is worthy of generating.
关键词
甲状旁腺功能亢进症 /
放射性核素显像 /
超声检查 /
体层摄影术 /
X线计算机
Key words
hyperparathyroidism /
radionuclide imaging /
ultrasonography /
tomography /
X-ray computed
陈维安;崔颖鹏;李春亿;梁 宏;胡 平.
99mTc-MIBI双时相显像诊断甲状旁腺功能亢进的临床价值[J]. 中国临床医学影像杂志. 2006, 17(3): 146-147
CHEN Wei-an;CUI Ying-peng;LI Chun-yi;LIANG Hong;HU Ping.
Clinical value of double phase 99mTc-MIBI imaging in diagnosing hyperparathyroidism[J]. Journal of China Clinic Medical Imaging. 2006, 17(3): 146-147
中图分类号：
R582.1
R817.4
R445.1
R814.42
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