摘要
目的:研究脂质沉积性肌病(LSM)的MRI表现,并评价MRI在LSM诊断中的应用价值。材料和方法:选择骨盆及双侧大腿肌肉,对9例LSM患者行MRI检查,采用自旋回波序列(SE)、快速自旋回波序列(FSE)及短时反转恢复序列(STIR)。结果:8例LSM患者的受累肌群均表现为片状短T1长T2异常信号,以臀肌及大腿后肌群受累为主,2例活动期患者的病变肌肉中尚混杂有斑片状长T1长T2异常信号影;1例无阳性表现。结论:LSM的MRI表现具有一定的特征性,受累肌群主要表现为脂肪沉积改变,在活动期,肌纤维可见斑片状坏死信号,病变双侧对称;MRI能为LSM的诊断、疗效判断及病情随访提供客观资料,并能为临床选取准确的活检部位提供定位。
Abstract
Objective: To investigate MRI findings of lipid storage myopathy(LSM), and evaluate the clinical value of MRI for LSM. Materials and Methods: Nine cases with LSM proved by biopsy underwent MRI of pelvis and thigh, spin echo sequence, fast spin echo sequence and short tau inversion recovery(STIR) were used. Results: The signal intensity of diseased muscle in 8 cases with LSM was hyperintense on T2WI and T1WI, and hyperintense signal intensity on T2WI and iso-intense on T1WI was seen on 2 patients as well. One patient had no positive findings. Conclusion: The MRI findings in LSM show certain characteristics: the involved muscles show lipid storage findings symmetrically, and the necrotic-like signal can be seen in the active stage as well. MRI can provide objective data for clinical diagnosis, therapeutic evaluation and follow-up. It can also help to decide the accurate site for biopsy.
关键词
肌疾病 /
磁共振成像
Key words
muscular diseases /
magnetic resonance imaging
郑贤应;慕容慎行;李银官;倪希和;曹代荣.
脂质沉积性肌病的MRI诊断[J]. 中国临床医学影像杂志. 2006, 17(8): 458-460
ZHENG Xian-ying;MURONG Shen-xing;LI Yin-guan;NI Xi-he;CAO Dai-rong.
Diagnosis of MRI in lipid storage myopathy[J]. Journal of China Clinic Medical Imaging. 2006, 17(8): 458-460
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
