老年退行性心脏瓣膜病与冠心病关系的研究

初洪钢; 余邦梅; 郭瑞强; 孙彬; 姜霞; 孙有刚

中国临床医学影像杂志 ›› 2007, Vol. 18 ›› Issue (1) : 26-28.

论著

老年退行性心脏瓣膜病与冠心病关系的研究

初洪钢1，余邦梅2，郭瑞强1，孙彬1，姜霞1，孙有刚1

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The study of the relationship between senile degenerative heart valvular disease and coronary artery disease

CHU Hong-gang1, YU Bang-mei2, GUO Rui-qiang1, SUN Bin1, JIANG Xia1, SUN You-gang1

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摘要

目的：探讨年龄≤65岁的患者中，老年退行性心脏瓣膜病（SDHVD）与冠心病之间的关系。方法：298例年龄≤65岁患者（其中122例年龄≤55岁，176例年龄＞55岁）同时进行冠状动脉造影检查和超声心动图检查。结果：①随着SDHVD钙化部位数的增加，患者年龄（P<0.01）、高血压（P<0.001）和糖尿病（P<0.05）的发病率均呈进行性增加；②随着SDHVD钙化部位数的增加，冠状动脉造影阳性的发生率逐渐增加（P<0.001）；③多因素Logistic回归分析发现，SDHVD是冠心病有价值的预测因子之一（P<0.01），且预测力大于年龄（P<0.05）和高脂血症（P<0.05）；对于女性患者和年龄≤55岁患者而言，SDHVD仍然是冠心病有价值的预测因子（P<0.05，P<0.001），而对于男性和年龄＞55岁患者而言，则无预测价值（P＞0.05）。结论：SDHVD可作为冠心病的预测因子，且钙化部位数越多，其预测价值越大。

Abstract

Objective: To determine whether there is an relation between senile degenerative heart valvular disease(SDHVD) with coronary artery disease(CAD) in subjects age≤65 years old. Methods: The age of the 298 patients were ≤65 years old. All patients underwent transthoracic echocardiography and coronary arteriography at the same time. Results: ①There was a progressive increase incidence of hypertension(P<0.001) and diabetes(P<0.05) with an increasing rate of calcium deposits of SDHVD as increase in age(P<0.001). ②With an increasing sites with calcium deposits of SDHVD, there was a progressive increase in positive results of coronary arteriography(P<0.001). ③Multiple logistic analyses identified SDHVD as significant predictors for the positive prevalence of coronary arteriography(P<0.01). In female patients and age ≤55 years, SDHVD was statistically significant predictors of the positive prevalence of coronary arteriography(P<0.001, P<0.05, respectively). Conclusions: There is a significant relation between SDHVD and coronary artery disease. The presence of SDHVD is an independent predictor of coronary artery disease.

导出引用

初洪钢;余邦梅;郭瑞强;孙彬;姜霞;孙有刚. 老年退行性心脏瓣膜病与冠心病关系的研究[J]. 中国临床医学影像杂志. 2007, 18(1): 26-28

CHU Hong-gang;YU Bang-mei;GUO Rui-qiang;SUN Bin;JIANG Xia;SUN You-gang. The study of the relationship between senile degenerative heart valvular disease and coronary artery disease[J]. Journal of China Clinic Medical Imaging. 2007, 18(1): 26-28

中图分类号： Ｒ542.5 Ｒ541.4 Ｒ540.45