超声造影与普通超声对兔腹主动脉再狭窄的动态观察

刘秋颖; 任卫东; 唐波

中国临床医学影像杂志 ›› 2008, Vol. 19 ›› Issue (11) : 779-781.

论著

超声造影与普通超声对兔腹主动脉再狭窄的动态观察

刘秋颖1，任卫东1，唐波2

作者信息 +

Dynamic observation of aortic restenosis in rabbits by contrast-enhanced ultrasonography and common ultrasonography

LIU Qiu-ying1, REN Wei-dong1, TANG Bo2

Author information +

文章历史 +

摘要

目的：对比观察超声造影和普通超声评价兔腹主动脉球囊损伤后再狭窄的应用价值，为随访再狭窄寻找新方法。方法：30只兔腹主动脉球囊损伤后即刻、3d、7d、14d、21d和28d时行普通超声检查，然后用SonoVue进行彩超造影和实时谐波造影，测量损伤处与上游管腔直径和收缩期峰值流速（PSV），计算狭窄率。结果：①损伤后即刻损伤处内径略增加，7d时开始变细（狭窄率22.30%），2周时狭窄程度达到高峰（狭窄率44.46%），之后不再增加。②谐波造影于7d时最早发现了轻度再狭窄，早于普通超声；谐波造影狭窄率与病理结果相关性最好（r=0.91），高于普通超声。③彩超造影较CDFI更准确地定位损伤部位。结论：超声造影能准确定位损伤部位、早期发现再狭窄，狭窄率测定准确度高，在随访再狭窄时有很高的应用价值。

Abstract

Objective: To compare the value of contrast-enhanced ultrasonography(CEUS) and common ultrasonography in follow-up of aortic restenosis in rabbits after balloon injury and to find a new method to observe restenosis. Methods: Thirty rabbits underwent CEUS and common ultrasonography instantly, on the 3rd, 7th, 14th, 21th and 28th days after abdominal aorta was injuried by balloon. Diameter and systolic peak velocity(PSV) of the injured segment and normal segment 2cm proximal to the abnormality were measured after injury and restenosis rate was calculated. Results: ①The diameter of the lesion increased instantly after injury and decreased on the 7th day. The restenosis rate reached the peak on the 14th day, and it didn’t change afterwards. ②Light restenosis was detected by CEUS on the 7th day, earlier than common ultrasonography. Stenosis rate measured with CEUS was well related with pathology, and the correlation coefficient of it was higher than that of common ultrasonography.③CEUS displayed turbulence more clearly than color Doppler. Conclusion: CEUS could detect restenosis early and accurately. Restenosis rate measured with CEUS is more accurate than common ultrasonography and it can do great help in follow-up of restenosis.

导出引用

刘秋颖;任卫东;唐波. 超声造影与普通超声对兔腹主动脉再狭窄的动态观察[J]. 中国临床医学影像杂志. 2008, 19(11): 779-781

LIU Qiu-ying;REN Wei-dong;TANG Bo. Dynamic observation of aortic restenosis in rabbits by contrast-enhanced ultrasonography and common ultrasonography[J]. Journal of China Clinic Medical Imaging. 2008, 19(11): 779-781

中图分类号： Ｒ543.1 Ｒ445.1