实时三维超声定量评价犬急性右室心肌缺血时室间隔功能

邓永怀; 张立敏; 任卫东; 马春燕; 陈昕

中国临床医学影像杂志 ›› 2008, Vol. 19 ›› Issue (5) : 319-321.

论著

实时三维超声定量评价犬急性右室心肌缺血时室间隔功能

邓永怀1，张立敏2，任卫东2，马春燕2，陈昕2

作者信息 +

Real-time three-dimensional echocardiographic quantitative assessment of the function of interventricular septum of canines in acute right ventricular myocardial ischemia

DENG Yong-huai1, ZHANG Li-min2, REN Wei-dong2, MA Chun-yan2, CHEN Xin2

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文章历史 +

摘要

目的：探讨实时三维超声（RT-3DE）定量评价犬急性右室心肌缺血时室间隔功能的价值。方法：18只犬，暴露心脏，于右冠状动脉阻断前后分别应用RT-3DE测量右室舒张末容积（RVEDV）、收缩末容积（RVESV）；左室舒张末容积（LVEDV）、收缩末容积（LVESV）；后间隔基底段、中间段的节段射血分数（rEF）。犬右冠状动脉阻断前为正常对照组，阻断后为实验组。结果：阻断右冠状动脉不影响室间隔血供，实验组RVEDV及RVESV均显著增加（P<0.05；P<0.01），LVEDV显著减小（P<0.05）；实验组后间隔的rEF较对照组显著降低（P<0.05）。结论：犬急性右室心肌缺血时室间隔的节段收缩功能减低。RT-3DE能无创定量评价犬急性右室心肌缺血时室间隔的节段收缩功能。

Abstract

Objective: To discuss the value of noninvasive real-time three-dimensional echocardiography(RT-3DE) evaluating the function of interventricular septum in acute right ventricular myocardial ischemia. Methods: Eighteen canines were used in this study. Right coronary artery ischemia was induced by occlusion at the proximal segment. Before RCA ischemia, the canines were used as the normal control group and after ischemia used as the experimental group. RT-3DE protocol was: before and during ischemia: the right ventricular end diastolic volume(RVEDV), left ventricular end diastolic volume(LVEDV), right ventricular end systolic volume(RVESV）, left ventricular end systolic volume(LVESV) were measured using RT-3DE fraction(rEF) of posterior interventricular with 3DQ advanced standard commercial software (Philips iE-33). At the meantime, regional ejection septum were calculated. Results: Blocking RCA did not affect the blood supply of the interventricular septum tissue. In IRCA group: RVEDV and RVESV were increased obviously(P<0.05), but LVEDV diminished obviously. Compared with the normal control group, rEF of posterior interventricular septum was decreased significantly in the IRCA group(P<0.05). Conclusions: rEF of posterior interventricular septum was decreased significantly when canines in acute right ventricular myocardial ischemia. RT-3DE can noninvasively quantify the function of interventricular septum in acute right ventricular myocardial ischemia.

导出引用

邓永怀;张立敏;任卫东;马春燕;陈昕. 实时三维超声定量评价犬急性右室心肌缺血时室间隔功能[J]. 中国临床医学影像杂志. 2008, 19(5): 319-321

DENG Yong-huai;ZHANG Li-min;REN Wei-dong;MA Chun-yan;CHEN Xin. Real-time three-dimensional echocardiographic quantitative assessment of the function of interventricular septum of canines in acute right ventricular myocardial ischemia[J]. Journal of China Clinic Medical Imaging. 2008, 19(5): 319-321

中图分类号： Ｒ542.2 Ｒ445.1