18F-FDG PET/CT显像在肝脏恶性肿瘤介入治疗后的临床应用价值

畅智慧; 刘兆玉; 李剑明; 孙洪赞; 单明

中国临床医学影像杂志 ›› 2008, Vol. 19 ›› Issue (9) : 642-645.

论著

18F-FDG PET/CT显像在肝脏恶性肿瘤介入治疗后的临床应用价值

畅智慧，刘兆玉，李剑明，孙洪赞，单明

作者信息 +

Clinical application of 18F-FDG PET/CT imaging after interventional treatments of hepatic malignancies

CHANG Zhi-hui, LIU Zhao-yu, LI Jian-ming, SUN Hong-zan, SHAN Ming

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文章历史 +

摘要

目的：探讨18F-FDG PET/CT显像在肝脏恶性肿瘤介入治疗后的临床应用价值。材料和方法：18例肝脏恶性肿瘤患者（男15例，女3例，年龄36～83岁，平均61.5岁）均在介入治疗后，临床症状或AFP检测怀疑残留或复发，但传统影像学检查未能明确病灶时行全身PET/CT检查，检查结果以最终病理结果或随访结局为参考。结果：最终共证实28处病灶，PET/CT检测出了93.7%（15/16例）的肝内病灶，100%（12/12例）的肝外病灶，总体检出率为96.4%。在15例中，PET/CT至少能检出1个病灶。结论：18F-FDG PET/CT显像有助于诊断肝脏恶性肿瘤介入治疗后传统影像学不能明确的肝内复发或新发病灶，并能同时有效地发现肝外病灶。

Abstract

Objective: To discuss the application of 18F-FDG PET/CT imaging after interventional treatment of hepatic malignancies. Materials and Methods: Eighteen patients(15 males and 3 females, 36~83 years old and 61.5 years old as an average) who underwent interventional treatments for hepatic malignancies were included in the study. A strong impression of tumor residual remaining or recrudescence was drawn according to clinical symptoms or AFP value but negative findings were got on conventional imaging. A whole body PET/CT examination was performed and the PET/CT results were compared with the final results of histology or close follow-up. Results: Twenty-eight foci were found and finally confirmed. 93.7%(15/16) of the foci inside liver and 100%(12/12) of the foci outside liver could be detected by PET/CT. The detection rate of PET/CT was 96.4%. 18F-FDG PET/CT was able to detect at least 1 lesion in 15 cases. Conclusion: 18F-FDG PET/CT not only can help to confirm those undetectable foci of hepatic malignancies on conventional imaging for recrudescence or newly-onset after interventional treatments, but also is able to show foci outside the liver parenchyma.

导出引用

畅智慧;刘兆玉;李剑明;孙洪赞;单明. 18F-FDG PET/CT显像在肝脏恶性肿瘤介入治疗后的临床应用价值[J]. 中国临床医学影像杂志. 2008, 19(9): 642-645

CHANG Zhi-hui;LIU Zhao-yu;LI Jian-ming;SUN Hong-zan;SHAN Ming. Clinical application of 18F-FDG PET/CT imaging after interventional treatments of hepatic malignancies[J]. Journal of China Clinic Medical Imaging. 2008, 19(9): 642-645

中图分类号： Ｒ735.7 Ｒ817.4