目的：本研究旨在设计用于盆腹部SPECT与CT图像融合的外基准支架，并以此实现SPECT/CT基于外标记的图像融合。方法：设计立体Ⅳ字型支架，并结合自行开发基于外标记的交互性通用图像融合软件，对标记带和结直肠癌的病灶SPECT/CT横断层图像进行配准及融合验证。结果：Ⅳ字型外标记支架易于固定，SPECT/CT显像过程中外标记点的相对位置不变；应用该标记支架实现了盆腹部病灶的SPECT/CT图像融合。结论：自行设计的适于盆腹部SPECT/CT图像配准的Ⅳ字型外标记物支架，易于固定，适于不同模态盆腹部横断层图像的配准融合。

Objective: To design pelvic and abdominal external fiducial marker frame for SPECT/CT rigid image registration and to complete image fusion. Methods: Ⅳ-shaped external marker frame was designed. Then the frame, combining the interactive general software that was based on external marker, which was empoldered by ourselves, was used to register and fuse validating the external marker frame and the recurrent lesions SPECT/CT transaction of patients with colorectal cancer. Result: The Ⅳ-shaped external marker frame could be easily fixed to the body, and the relative position of external marker point maintains in the same station during the different scanning procedure by SPECT/CT. With combination of marker frame and the image fusion software based on that, the recurrent lesions of colorectal cancer SPECT/CT image fusion was accomplished on a low cost PC. Conclusion: The Ⅳ-shaped external marker frame suited to the image fusion software of pelvic and abdominal SPECT/CT we designed could be easily fixed to the body, which was qualified to multi-modal transaction image fusion.