白质纤维束成像在脑星形胶质细胞瘤中的作用

贾中正; 李敏; 曹亮; 汤乐民

中国临床医学影像杂志 ›› 2009, Vol. 20 ›› Issue (4) : 240-242.

论著

白质纤维束成像在脑星形胶质细胞瘤中的作用

贾中正1，李敏1，曹亮1，汤乐民2

作者信息 +

Application of diffusion tensor tractography in brain astrocytomas

JIA Zhong-zheng1, LI Min1, CAO Liang1, TANG Le-min2

Author information +

文章历史 +

摘要

目的：探讨白质纤维束成像（Diffusion tensor tractography，DTT）技术在脑星形胶质细胞瘤研究中的价值。材料与方法：对33例经病理证实的脑星形胶质细胞瘤患者进行常规MR成像、弥散张量成像（DTI）和DTT，分析肿瘤瘤周白质纤维束的改变形式与肿瘤分级的关系。结果：无论是高级别还是低级别肿瘤，瘤周白质纤维束都可以发生移位（77.78%~100%），而白质纤维束的破坏和中断主要与星形胶质细胞瘤的恶性程度有关，随着肿瘤级别的升高，白质纤维束的破坏和中断的发生率也逐渐升高（7.69%~72.73%）。结论：DTT技术在显示脑星形胶质细胞瘤分级方面有重要的价值。

Abstract

Objective: To evaluate the value of diffusion tensor tractography(DTT) in brain astrocytomas. Materials and Methods: Thirty-three patients with histologically confirmed astrocytomas underwent routine MRI, DTI, DTT, analyzing the changes of white matter fibres around the tumors and specific conditions in different grade of astrocytomas. Results: There is displacement of white matter fibres around tumors whether low-grade tumors or high-grade tumors(77.78%~100%). Disruption and interruption of white matter fibres around tumors are related to malignancy of astrocytomas. The higher the grade of tumor, the higher incidence rate of white matter disruption and interruption are(7.69%~72.73%). Conclusion: DTT plays an important role in revealing the grade of brain astrocytomas.

导出引用

贾中正;李敏;曹亮;汤乐民. 白质纤维束成像在脑星形胶质细胞瘤中的作用[J]. 中国临床医学影像杂志. 2009, 20(4): 240-242

JIA Zhong-zheng;LI Min;CAO Liang;TANG Le-min. Application of diffusion tensor tractography in brain astrocytomas[J]. Journal of China Clinic Medical Imaging. 2009, 20(4): 240-242

中图分类号： Ｒ739.41 Ｒ445.2