摘要
目的：应用新型超声造影剂SonoVue观察肾细胞癌超声造影血流灌注特点，术后分析其病理特点。方法：对42例肾细胞癌患者术前进行超声造影检查，观察造影剂开始显影、达峰及消退的全过程，并用ACQ软件分析时间-强度曲线数值。结果：28个肾透明细胞癌超声造影呈富血供表现，时间－强度曲线分析显示透明细胞癌的ΔAT、ΔTTP低于其他两组，其ΔPI和ΔI60s明显高于其他两组，即“快进慢退高增强”的造影模式。另外3个肾透明细胞癌及所有的嫌色细胞癌和乳头状癌呈乏血供表现，嫌色细胞癌和乳头状癌的AT、TTP慢于周边肾组织，PI和I60低于周边肾组织，呈“慢进低增强”的造影特点。结论：实时超声造影能够提供不同肾细胞癌微血管灌注特征，为肾细胞癌的诊断及鉴别诊断提供了更多的参考依据，有较高的临床应用价值。
Abstract
Objective: To observe the perfusion characteristics of contrast-enhanced ultrasound(CEUS) in renal cell carcinoma(RCC) by a new contrast agent SonoVue, and to analyze the pathological characteristics of RCC after operation. Methods: Forty-two cases of RCC were examined by the CEUS before operation, we observed the beginning of contrast agent enhancement, the peak and the dissipation as a whole, and analyzed the time-intensity curve(TIC) with ACQ software. Results: Twenty-eight clear cell renal cell carcinoma(CCRCC) cases showed rich blood supply, the results of TIC showed ΔAT and ΔTTP were smaller than the other two groups, the ΔPI and ΔI60s were significantly higher than the other two groups, that was “fast-in and slow-out and high enhance” contrast mode. Other 3 CCRCC cases, all the chromophobe carcinomas and papillary carcinomas showed low blood supply performance. The AT and TTP of chromophobe carcinomas and papillary carcinomas were slower than the surrounding renal tissue, the PI and I60s were lower than the surrounding renal tissue, that was “slow-in and low enhance” contrast characteristics. Conclusion: Real-time CEUS can provide more micro-perfusion characteristics in RCC. It provides more reference of the diagnosis and differential diagnosis in RCC, which has a higher clinical value.
关键词
肾肿瘤 /
病理学 /
超声检查 /
多普勒 /
彩色
Key words
Kidney neoplasms /
Pathology /
Ultrasonography /
Doppler /
color
顾继英;张学梅;白 敏;杜联芳;李 凡;张会萍.
肾细胞癌超声造影与病理对照分析研究[J]. 中国临床医学影像杂志. 2010, 21(2): 90-93
GU Ji-ying;ZHANG Xue-mei;BAI Min;DU Lian-fang;LI Fan;ZHANG Hui-ping.
Analysis of the relationship between the contrast-enhanced ultrasound and pathology of renal cell carcinoma[J]. Journal of China Clinic Medical Imaging. 2010, 21(2): 90-93
中图分类号：
Ｒ737.11
Ｒ365.73
Ｒ445.1
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