健康成年人大脑皮层MRI弥散加权像的信号差异研究

朱建忠; 赵雷; 秦 健; 程玉卉; 刘军杰

中国临床医学影像杂志 ›› 2010, Vol. 21 ›› Issue (3) : 164-167.

论著

健康成年人大脑皮层MRI弥散加权像的信号差异研究

朱建忠1，赵雷1，秦健2，程玉卉1，刘军杰2

作者信息 +

Study of signal variation on diffusion-weighted MRI of cerebral cortices in healthy adults

ZHU Jian-zhong1, ZHAO Lei1, QIN Jian2, CHENG Yu-hui1, LIU Jun-jie2

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文章历史 +

摘要

目的：测定健康成年人大脑皮层是否有区域性MRI弥散信号差异。材料和方法：使用Signa HDe 1.5T超导磁共振评定47名神经系统健康的自愿者（男27名，女20名，年龄31~82岁）大脑皮层各区域的弥散加权像（DWI）信号强度（SI）、信噪比（CNR）和表观弥散系数（ADC）值。结果：大脑皮层扣带回和岛叶DWI SI与年龄无关，经检验与年龄和左右大脑半球差别都无统计学意义（P>0.05），大脑皮层CNRs在不同皮层区域信号差别有显著的统计学意义（P<0.001）；扣带回和岛叶内信号明显比其他部位高（P<0.01），大脑皮层各部位皮层ADC男女之间差异无统计学意义（P>0.05）。结论：正常人大脑皮质弥散图像扣带回和岛叶常显示为高信号，有助于避免将正常脑组织的弥散高信号误诊为病理异常信号。

Abstract

Objective: To determine whether there is regional signal variation in the brain cortices of neurologically healthy adults on DW-MR images. Materials and Methods: The signal intensity(SI) on DW-MR images, contrast-to-noise ratios(CNR), and apparent diffusion coefficient(ADC) maps of the cerebral cortices at Signa HDe 1.5T were evaluated in 47 neurologically healthy subjects(27 men, 20 women, age range 31~82 years). Results: Increased SI on DW-MR images was seen in the cingulate gyrus and insula regardless of patient age. There were no statistically significant gender-or laterality-related differences(P>0.05). There was statistically significant differences existed in CNR among the cortical regions(P<0.001), and the signal intensity was higher in the cingulate gyrus and insula than in the other cortices(P<0.01). There were no apparent ADC differences among the cortices on ADC maps in males and females(P>0.05). Conclusion: The signal of brain cortices in the cingulate gyrus and insula was observed on DW-MR images of healthy subjects, and frequently manifest high SI. These findings may help in the recognition of cortical signal abnormalities as visualized on DW-MR images.

导出引用

朱建忠;赵雷;秦健;程玉卉;刘军杰. 健康成年人大脑皮层MRI弥散加权像的信号差异研究[J]. 中国临床医学影像杂志. 2010, 21(3): 164-167

ZHU Jian-zhong;ZHAO Lei;QIN Jian;CHENG Yu-hui;LIU Jun-jie. Study of signal variation on diffusion-weighted MRI of cerebral cortices in healthy adults[J]. Journal of China Clinic Medical Imaging. 2010, 21(3): 164-167

中图分类号： Ｒ338.25 Ｒ445.2