99Tcm-phytate乳腺癌前哨淋巴结显像影响因素的研究

魏玲格; 百濑充浩; 角谷真澄

中国临床医学影像杂志 ›› 2010, Vol. 21 ›› Issue (6) : 385-387.

论著

99Tcm-phytate乳腺癌前哨淋巴结显像影响因素的研究

魏玲格1，百濑充浩2，角谷真澄2

作者信息 +

The research of influence factor for breast sentinel lymphoscintigraphy with 99Tcm-phytate

WEI Ling-ge1, MOMOSE Mitsuhiro2, KADOYA Masumi2

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文章历史 +

摘要

目的：分析99Tcm-phytate乳腺癌前哨淋巴结（SLN）显像时，患者年龄、肿瘤部位、大小及注射位置是否影响乳腺癌SLN显像的成功率。方法：手术前日在乳腺癌皮下注射0.2ml及肿瘤两侧（3、9点或6、12点）各注射99Tcm-phytate 0.1ml（122MBq/ml），注射示踪剂后5min、2h分别用单光子发射计算机断层仪（SPECT）行早期及延迟SLN显像。结果采用SPSS 11.5软件进行统计学处理，行χ2检验。结果：210例患者中，204例患者5min及?蛐或2h显像阳性，成功率为97.1%。乳腺癌所在的部位、大小、注射位置5min及2h显像均无统计学意义。年龄≤50岁和年龄＞50岁患者5min SLN显像阳性率分别为59.4%，44.7%（χ2＝4.03，P＜0.05）；2h SLN显像阳性率，年龄≤50岁和年龄＞50岁的分别为98.5%，90.7%（χ2＝4.49，P＜0.05）。结论：乳腺癌SLN显像的成功率不受乳腺癌所在的部位、大小、注射位置的影响，而年龄对其成功率有一定的影响。

Abstract

Objective: Variable success rates for identifying axillary sentinel lymph node(SLN) in breast cancer patients using preoperative lymphoscintigraphy have been reported. We evaluated whether tumor location, size, method of interval and age affect its success in identifying SLN. Method: Preoperative breast lymphoscintigraphy was performed in consecutive breast cancer patients. Imaging at 5 minuties and 2 hours after peritumoral injection of 99Tcm-phytate. Chi-Square test for statistics was used with SSPS 11.5 software. Results: SLN were obtained in 204(97.1%) at 5 minuties and?蛐or 2 hours of 210 patients. Success in identifying SLN was not affected by tumor location, size, method of interval; SLN were identified significantly more frequently in patients under 50 years old(59.4%) than those over 50 years old(44.7%)(χ2＝4.03, P＜0.05) at 5 minutes; 98.5% and 90.7%(χ2＝4.49, P＜0.05) at 2 hours. Conclusion: 99Tcm-phytate SLN scintigraphy is an easy technique with an acceptable success rate. No effect of tumor size, location, method of interval was found. Patient age affected its success in identifying SLN.

导出引用

魏玲格;百濑充浩;角谷真澄. 99Tcm-phytate乳腺癌前哨淋巴结显像影响因素的研究[J]. 中国临床医学影像杂志. 2010, 21(6): 385-387

WEI Ling-ge;MOMOSE Mitsuhiro;KADOYA Masumi. The research of influence factor for breast sentinel lymphoscintigraphy with 99Tcm-phytate[J]. Journal of China Clinic Medical Imaging. 2010, 21(6): 385-387

中图分类号： Ｒ737.9 Ｒ817.4