双源CT双能扫描测量骨密度的实验研究

蒋宝国;李松柏;陈晓朝;宣 扬;鲍 楠;康 彦;卑贵光;李 响

中国临床医学影像杂志 ›› 2010, Vol. 21 ›› Issue (6) : 405-408.

中国临床医学影像杂志 ›› 2010, Vol. 21 ›› Issue (6) : 405-408.
论著

双源CT双能扫描测量骨密度的实验研究

  • 蒋宝国1,李松柏1,陈晓朝2,宣 扬2,鲍 楠2,康 彦2,卑贵光1,李 响1
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An experimental study of dual source CT approach measuring bone mineral density

  • JIANG Bao-guo1, LI Song-bai1, CHEN Xiao-zhao2, XUAN Yang2, BAO Nan2, KANG Yan2, BEI Gui-guang1, LI Xiang1
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摘要

目的:评价双源CT(DSCT)双能骨密度测量方法的准确性。方法:自行设计开发的DSCT双能CT定量法(DEQCT)骨密度测量软件,与临床上广泛应用的双能骨密度测量仪(DEXA)及理论单能定量CT测量法(SEQCT)骨密度测量方法分别测定猪腰脊椎骨骨密度,并将测量值同猪脊骨煅烧后的骨密度值进行比较,观察哪种测量方法更准确。结果:DEQCT方法测量值[(0.5023±0.0353)g/cm3]最为接近煅烧值[(0.5050±0.0434)g/cm3],两者间差别不具有统计学意义,理论SEQCT140kV方法测量值[(0.4813±0.0314)g/cm3]小于煅烧值及双能测量值,两两间的差别均具有统计学差别。DEXA所测量值[(0.4527±0.0360)g/cm2]明显小于煅烧值及DEQCT和理论SEQCT140kV法测量值,且与三者的差别均存在统计学意义。结论:DSCT双能骨密度测量方法优于临床应用的SEQCT骨密度测量方法及DEXA测量法。

Abstract

Objective: To evaluate the accuracy of DEQCT in determining bone mineral density(BMD) by using dual source CT(DSCT). Methods: BMD of the lumbar vertebral body of pig was measured by our designing software, DEQCT, at DSCT and by SEQCT software of the Neusoft and DEXA. The lumbar body of pig was then calcined, the lime of the calcined material was measured. The measuring results of DEQCT, SEQCT140kV and DEXA were compared. Results: The BMD of the vertebral body and the calcined material measured by DEQCT was (0.5050±0.0434)g/cm3, and (0.5023±0.0353)g/cm3 respectively, there was no significant difference(P=0.779). BMD measured by SEQCT140kV[(0.4813±0.0314)g/cm3] was significantly lower than the measurement of the calcined material. BMD determined by DEXA[(0.4527±0.0360)g/cm2] was significantly lower than the measurement of calcined material and also significantly lower than the results measured by DEQCT and SEQCT(P<0.05). Conclusion: BMD determined by DEQCT at DSCT is superior to SEQCT and DEXA approach.

关键词

骨密度 / 体层摄影术 / X线计算机

Key words

Bone density / Tomography / X-ray computed

引用本文

导出引用
蒋宝国;李松柏;陈晓朝;宣 扬;鲍 楠;康 彦;卑贵光;李 响. 双源CT双能扫描测量骨密度的实验研究[J]. 中国临床医学影像杂志. 2010, 21(6): 405-408
JIANG Bao-guo;LI Song-bai;CHEN Xiao-zhao;XUAN Yang;BAO Nan;KANG Yan;BEI Gui-guang;LI Xiang. An experimental study of dual source CT approach measuring bone mineral density[J]. Journal of China Clinic Medical Imaging. 2010, 21(6): 405-408
中图分类号: R336    R814.42   

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