遗传性痉挛性截瘫伴薄胼胝体的影像学表现

李晓东; 高佩虹; 王贵宾; 车峰远; 王金亮; 高乃永; 王桂玲

中国临床医学影像杂志 ›› 2010, Vol. 21 ›› Issue (7) : 465-468.

论著

遗传性痉挛性截瘫伴薄胼胝体的影像学表现

李晓东1，高佩虹2，王贵宾2，车峰远2，王金亮2，高乃永2，王桂玲2

作者信息 +

The imaging characteristics of hereditary spastic paraplegia with thin corpus callosum

LI Xiao-dong1, GAO Pei-hong2, WANG Gui-bin2, CHE Feng-yuan2, WANG Jin-liang2, GAO Nai-yong2, WANG Gui-ling2

Author information +

文章历史 +

摘要

目的：分析遗传性痉挛性截瘫伴薄胼胝体（HSP-TCC）的影像学特点，以提高对此病的认识。方法：结合文献复习并报告一家族3例HSP-TCC患者的影像学表现。结果：本组3例HSP-TCC患者均显示胼胝体菲薄、颈胸髓明显变细，内见长T2信号、弥漫性非特异性脑白质病变和轻度脑萎缩。结论：HSP-TCC可广泛影响中枢神经系统，MRI特异性表现包括薄胼胝体，侧脑室周围白质长T2信号，脊髓萎缩及信号异常及后期出现轻度到中度脑萎缩。

Abstract

Objective: To analyze the imaging characteristics of hereditary spastic paraplegia with thin corpus callosum(HSP-TCC), so as to get a better understanding of the disease. Methods: Three patients from the same family with HSP-TCC were reported with reviewing of the literature. Results: Thin corpus callosum, long T2 signal in the thinning cervical and thoracic spinal cord were seen. Diffused unspecific white matter lesions with mild brain atrophy, were also seen in the three HSP-TCC cases of this group. Conclusion: The central nervous system may be affected extensively by HSP-TCC, characteristic MRI signs including thin corpus callosum, long T2 signal in the white matter around lateral ventricle and in the spinal cord, atrophy and abnormal signal of the spinal cord, as well as subsequent mild or moderate brain atrophy.

导出引用

李晓东;高佩虹;王贵宾;车峰远;王金亮;高乃永;王桂玲. 遗传性痉挛性截瘫伴薄胼胝体的影像学表现[J]. 中国临床医学影像杂志. 2010, 21(7): 465-468

LI Xiao-dong;GAO Pei-hong;WANG Gui-bin;CHE Feng-yuan;WANG Jin-liang;GAO Nai-yong;WANG Gui-ling. The imaging characteristics of hereditary spastic paraplegia with thin corpus callosum[J]. Journal of China Clinic Medical Imaging. 2010, 21(7): 465-468

中图分类号： Ｒ746 Ｒ445.2