摘要
目的：探讨磁共振扩散加权成像（DWI）评估前列腺癌分期的价值，以及表观扩散系数（ADC）值与病理分级的相关性。材料与方法：使用Philips Achieva 3.0T高场强超导型磁共振和腹部多通道相控阵线圈，对46例前列腺癌患者行DWI检查，并测量ADC值。结果：对前列腺癌分期的诊断准确性，T2WI组为80%，DWI组为83%，DWI＋T2WI组为89%，各组AZ值分别为0.82、0.83和0.91，DWI+T2WI组明显高于其它组（P=0.02、0.04）。ADC均值：G1组为1.31×103mm，G2组为1.14×103mm，G3组为0.7×103mm，G3组平均ADC值低于G1和G2组（P<0.05）。结论：3.0T高场强DWI联合T2WI成像，可明显提高前列腺癌分期的准确性，ADC值能够预测肿瘤的病理分级。
Abstract
Objective: To evaluate the ability of DWI in determining the stage of prostate cancer(PCA), and to measure the correlation between apparent diffusion coefficient(ADC) with histologic grade. Materials and Methods: Forty-six patients underwent DWI with a 3.0T MR scanner using a pelvic array multi-coil. The ADC values of PCA were calculated. Results: The overall accuracy of T stage diagnosis was 80% for T2WI alone, 83% for DWI alone, 89% for T2WI plus DWI. The AZ value was significantly higher(P=0.02, 0.04) for DWI plus T2WI(AZ=0.91) than for T2WI alone(AZ=0.82) and for DWI alone(AZ=0.83). The mean ADC of G1 tumors was 1.31×103mm, 1.14×103mm for G2, 0.7×103mm for G3, The mean ADC of G3 tumors was lower than that of G1 and G2 tumors(P<0.05). Conclusion: Combined T2WI and DWI is better than DWI alone and T2WI alone in the accuracy of T stage diagnosis. The ADC value may predict the histologic grade of PCA.
关键词
前列腺肿瘤 /
肿瘤分期 /
磁共振成像 /
弥散
Key words
Prostatic neoplasms /
Neoplasm staging /
Diffusion magnetic resonance imaging
周国兴;曹开明;王轶斌;赵江民;郝楠馨.
3.0T MR扩散加权成像评估前列腺癌分期、分级的价值[J]. 中国临床医学影像杂志. 2010, 21(7): 490-492
ZHOU Guo-xing;CAO Kai-ming;WANG Yi-bin;ZHAO Jiang-min;HAO Nan-xin.
Accuracy of 3.0T diffusion-weighted MRI for diagnosing the stage and grade of prostate cancer[J]. Journal of China Clinic Medical Imaging. 2010, 21(7): 490-492
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