摘要
目的：探讨320排全脑动态容积CT血管造影及灌注成像在烟雾病中的应用价值。方法：18例烟雾病患者均行320排全脑动态容积CT扫描，并利用容积再现（VR）技术进行图像重组且采用电影模式观看，同时完成全脑灌注成像检查。结果：所有病例均获得良好的平扫容积图像、动态DSA图像及全脑灌注图像，均清晰显示发生狭窄、闭塞的颈内动脉及颅底异常血管网，其中双侧颈内动脉闭塞9例，单侧颈内动脉闭塞2例，单侧大脑中动脉闭塞7例，侧支血管表现为相应血管及其分支的粗大、增多及迂曲延长。全脑灌注图像中，显示平均通过时间（MTT）延长，为0.5~13.0s；局部脑血流量（rCBF）下降10例，降低幅度为26.0%~54.5%；局部脑血容量（rCBV）显示有8例在正常范围内，4例出现不同程度的降低（30.0%~68.5%）。结论：320排全脑动态容积CT成像可以动态观察颅内血管的形态及动态血流信息，全脑灌注图像可以量化评价烟雾病患者全脑灌注情况，真正实现了全脑一站式容积扫描，对于烟雾病的诊断和评价脑组织血供具有极高的临床应用价值。
Abstract
Objective: To evaluate the value of 320-slice whole brain dynamic volume CT angiography and CT perfusion imaging in moyamoya disease. Methods: Eighteen cases with moyamoya disease were examined with 320-slice whole brain dynamic volume CT. Imaging data were generated with volume rendering reconstruction and display in cine mode, and complete CT perfusion imaging were performed simultaneously. Results: We succeeded in obtaining plain images of whole-brain, dynamic CTA and whole-brain perfusion images in 18 patients, all of which showed lesions of stenosis and obstruction in internal carotid artery (ICA), proximum of Willis circle and posterior and middle cerebral arteries; abnormal vessel network in the basal part of brain; and the condition of collateral circulation in the brain. Perfusion weighted imaging revealed mean transit time(MTT) was extended(0.5~13s). Ten cases showed decrease in regional cerebral blood flow(rCBF), the amplitude was 26.0%~54.5%. There were 8 cases of normal and 4 cases decreased in regional cerebral blood volume(rCBV). Conclusion: Whole brain dynamic volume imaging with 320-detector row CT can provide 3D structure of vessels of the whole brain, and serial of the dynamic blood flow and cerebral perfusion in a single scanning, which has the potential diagnostic value in moyamoya disease.
关键词
脑底异常血管网病 /
体层摄影术 /
螺旋计算机 /
血管造影术
Key words
Moyamoya disease /
Tomography /
spiral computed /
Angiography
潘宇宁;黄求理;叶贤旺;张 杰;廉艳东;傅芬芬.
320排全脑动态容积CT血管造影及灌注成像在烟雾病中的应用[J]. 中国临床医学影像杂志. 2011, 22(12): 840-843
PAN Yu-ning;HUANG Qiu-li;YE Xian-wang;ZHANG Jie;LIAN Yan-dong;FU Fen-fen.
Experience of 320-slice whole brain dynamic volume CT and perfusion imaging in patients with moyamoya disease[J]. Journal of China Clinic Medical Imaging. 2011, 22(12): 840-843
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