摘要
目的：应用二维斑点追踪成像（Two-dimensional speckle tracking imaging，2DSTI）技术测量2型糖尿病（Type 2 diabetes mellitus，T2DM）患者左室心肌旋转指标，探讨2DSTI技术评价T2DM患者左室心肌旋转运动的临床价值。方法：采集43例T2DM患者（无微血管病变组20例，合并微血管病变组23例）和30例正常人的左室短轴二尖瓣水平、心尖水平切面二维高帧频声像图，测量内膜下（Prot-endo）、外膜下（Prot-epi）、切面整体（Prot）及跨壁角度梯度峰值（Prot-mur）。结果：①从正常对照组到糖尿病合并微血管病变组心尖水平Prot-endo、Prot-epi、Prot、二尖瓣水平Prot-epi递增（P＜0.05），而心尖水平Prot-mur递减（P＜0.05）；②糖尿病合并微血管病变组的二尖瓣水平Prot-endo较正常对照组增高（P＜0.05）；③与正常对照组比较，糖尿病患者的二尖瓣水平Prot-mur减低、二尖瓣水平Prot增高（P＜0.05）。结论：2DSTI技术能够准确测量T2DM患者左室短轴二尖瓣水平、心尖水平切面Prot-endo、Prot-epi、Prot及Prot-mur的变化，敏感评价T2DM患者心功能状态。
Abstract
Objective: To observe the rotation parameter of left ventricular short-axis views in the subendocardial and subepicardial myocardium layers by two-dimensional speckle tracking imaging(2DSTl), and to evaluate its performance in patients with type 2 diabetes mellitus(T2DM)． Methods: Fourty-three patients with T2DM(20 patients without microangiopathy, 23 patients with microangiopathy), and 30 cases of healthy volunteers as control were included in the study． High frame rate dynamic two-dimensional images were recorded at the left ventricular short-axis view, including basal and apical planes． The peak subendocardial rotation(Prot-endo), peak subepicardial rotation(Prot-epi), peak bulk rotation(Prot), and peak mural rotation(Prot-mur) were measured． Results: ①The apical Prot-endo, Prot-epi, Prot and the basal Prot-epi were higher and the apical Prot-mur was lower in control group than the T2DM group with microangiopathy(P＜0.05). ②The basal Prot-endo of T2DM patients with microangiopathy was significantly lower than that in control group. ③When compared to the control group, the basal Prot-mur decreased while the basal Prot increased in the T2DM group(P＜0.05)． Conclusions: The 2DSTI can accurately evaluate the characteristics of left ventricular rotation parameter and sensitively evaluate the cardiac function in patients with T2DM.
关键词
糖尿病 /
2型 /
心室功能 /
左 /
心肌 /
超声心动描记术 /
多普勒 /
彩色
Key words
Diabetes mellitus /
type 2 /
Ventricular function /
left /
Myocardium /
Echocardiography /
Doppler /
color
谢 天;李沿江;栾智勇;杨毓雯.
二维斑点追踪成像技术评价2型糖尿病患者左室内、外膜下心肌旋转[J]. 中国临床医学影像杂志. 2012, 23(10): 703-706
XIE Tian;LI Yan-jiang;LUAN Zhi-yong;YANG Yu-wen.
Evaluation of endocardial and epicardial rotation in type 2 diabetes mellitus patients by two-dimensional speckle tracking imaging[J]. Journal of China Clinic Medical Imaging. 2012, 23(10): 703-706
中图分类号：
Ｒ587.1
Ｒ331.31
Ｒ540.45
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