摘要
目的：本研究旨在探讨18F-FDG PET-CT对转移瘤患者原发灶诊断中的价值。方法：回顾性分析164例经病理学检查证实为转移的不明原发灶肿瘤患者为寻找原发灶而行18F-FDG PET-CT检查，待最终随访结束后对所有数据、资料进行统计处理分析。结果：18F-FDG PET-CT对肿瘤原发灶总检出率为51.2%（84/164），特异性97.3%（71/73），敏感性92.3%（84/91），准确度94.5%（155/164），阴性预测值91.0%（71/78），阳性预测值97.7%（84/86）。PET-CT对转移性腺癌、转移性鳞癌、转移性未分化癌3组常见病理类型转移瘤的原发灶检出率分别为54.0%（47/87）、56.8%（21/37）、40.0%（12/30）。经统计分析，3组转移瘤原发灶检出率之间无统计学差异。结论：18F-FDG PET-CT在寻找不明原发灶肿瘤原发灶中具有重要价值。
Abstract
Objective: To evaluate the 18F-FDG PET-CT in detecting primary foci in cases of suspected metastatic tumor. Methods: One hundred and sixty-four patients with pathologically proved metastasis of unknown primary tumor underwent 18F-FDG PET-CT scan. Statistical analysis was performed after the final follow up. Result: The total positive rate, specificity, sensitivity, accuracy, negative predictive value and positive predictive value were 51.2%(84/164), 97.3%(71/73), 92.3%(84/91), 94.5%(155/164), 91.0%(71/78), 97.7%(84/86) respectively. The positive rate of the primary foci for metastatic adenocarcinoma, metastatic squamous carcinoma and metastatic undifferentiated carcinoma were 54.0%(47/87), 56.8%(21/37) and 40.0%(12/30) respectively. According to the statistical analysis, there was no statistical difference among the positive rate of the three groups. Conclusion: 18F-FDG PET-CT might be of importance in the detection of primary site in unknown primary tumors
关键词
肿瘤 /
未知原发灶 /
氟脱氧葡萄糖F18 /
正电子发射断层显像术 /
体层摄影术 /
螺旋计算机
Key words
Neoplasms /
unknown primary /
Fluorodeoxyglucose F18 /
Positron-emission tomography /
Tomography /
spiral computed
葛 冉;赵丽霞;田 蓉;苏鸣岗;李 林.
18F-FDG PET-CT在寻找转移瘤原发灶中的临床价值[J]. 中国临床医学影像杂志. 2012, 23(10): 722-726
GE Ran;ZHAO Li-xia;TIAN Rong;SU Ming-gang;LI Lin.
The role of 18F-FDG PET-CT in the detection of primary lesions for patients with tumor metastasis[J]. Journal of China Clinic Medical Imaging. 2012, 23(10): 722-726
中图分类号：
Ｒ73-37
Ｒ817.4
Ｒ814.42
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
