11C蛋氨酸PET/CT与MRI对脑胶质瘤术前诊断价值的比较研究

王 如;钱立庭;汪世存;展凤麟;潘 博;张红雁;马 军

中国临床医学影像杂志 ›› 2012, Vol. 23 ›› Issue (11) : 766-768.

中国临床医学影像杂志 ›› 2012, Vol. 23 ›› Issue (11) : 766-768.
论著

11C蛋氨酸PET/CT与MRI对脑胶质瘤术前诊断价值的比较研究

  • 王 如,钱立庭,汪世存,展凤麟,潘 博,张红雁,马 军
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Comparison of 11C-MET PET/CT and MRI for the diagnosis of gliomas before operation

  • WANG Ru, QIAN Li-ting, WANG Shi-cun, ZHAN Feng-lin, PAN Bo, ZHANG Hong-yan, MA Jun
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摘要

目的:探讨11C-MET PET/CT对脑胶质瘤的术前诊断价值。方法:11例经MRI检查后拟诊胶质瘤的术前患者接受11C-MET PET/CT检查,将结果与术后病理比较。结果:11例患者中,1例术后病理为胶质细胞增生,其余10例均确诊为胶质瘤。11C-MET PET/CT与MRI在术前诊断脑胶质瘤的敏感性、特异性和准确性分别为100%、100%、100%和100%、0、91%。结论:11C-MET PET/CT对脑胶质瘤的术前诊断价值优于MRI。

Abstract

Objective: To evaluate the value of 11C-MET PET/CT and MRI for the diagnosis of gliomas before operation. Methods: We examined 11 patients prospectively with newly diagnosed gliomas based on brain MRI before operations. 11C-MET PET/CT was performed on these patients and then compared with their histological analysis. Results: Of all the eleven patients, ten were confirmed to be gliomas, except one glial cell hyperplasia. The sensitivity, specificity and accuracy of 11C-MET PET/CT and MRI for diagnosis of gliomas before operation were 100%, 100%, 100% and 100%, 0, 91%, respectively. Conclusion: 11C-MET PET/CT is more helpful than MRI for diagnosis of gliomas before operation.

关键词

神经胶质瘤 / 脑肿瘤 / 正电子发射断层显像术 / 磁共振成像

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王 如;钱立庭;汪世存;展凤麟;潘 博;张红雁;马 军. 11C蛋氨酸PET/CT与MRI对脑胶质瘤术前诊断价值的比较研究[J]. 中国临床医学影像杂志. 2012, 23(11): 766-768
WANG Ru;QIAN Li-ting;WANG Shi-cun;ZHAN Feng-lin;PAN Bo;ZHANG Hong-yan;MA Jun. Comparison of 11C-MET PET/CT and MRI for the diagnosis of gliomas before operation[J]. Journal of China Clinic Medical Imaging. 2012, 23(11): 766-768
中图分类号: R730.264    R739.41    R817.4    R445.2   

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