多形性黄色星形细胞瘤的影像表现

陈小东; 刘含秋; 陆 健; 缪小芬; 张学琴; 梁宏伟; 张 涛; 程 斌; 姜吉锋

中国临床医学影像杂志 ›› 2012, Vol. 23 ›› Issue (8) : 533-537.

论著

多形性黄色星形细胞瘤的影像表现

陈小东1，刘含秋2，陆健1，缪小芬1，张学琴1，梁宏伟1，张涛1，程斌1，姜吉锋1

作者信息 +

Imaging findings of pleomorphic xanthoastrocytomas

CHEN Xiao-dong1, LIU Han-qiu2, LU Jian1, MIAO Xiao-fen1, ZHANG Xue-qin1, LIANG Hong-wei1, ZHANG Tao1, CHENG Bin1, JIANG Ji-feng1

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摘要

目的：探讨多形性黄色星形细胞瘤（PXA）的影像特征。方法：回顾性分析经手术病理证实的12例PXA的影像表现，其中10例行MR检查，2例同时行CT及MR检查。结果：12例患者共有13枚病灶，颞叶6枚，颞叶为主累及多个脑叶4枚，岛叶2枚，额叶1枚。13枚病灶中囊实性5枚，囊伴结节型6枚，实性结节2枚。增强后实性区及壁结节有明显强化，囊伴结节型病灶囊壁均不强化。13枚病灶中2枚出现邻近软脑膜强化，1枚有钙化。6枚行DWI检查的病灶中，表观弥散系数（ADC）值均高于对侧相应正常区，其中2例WHO Ⅲ级PXA的ADC值及相对表观弥散系数（rADC）值明显低于另外4例WHO Ⅱ级PXA。2枚行1H-MRS检查的病灶中，实性部分Cho峰升高，NAA峰下降，Cho/NAA值为0.84、1.06，1例出现Lac峰。结论：PXA的影像表现有一定特征性，认识这些特征并结合MR多种功能成像技术，有助于正确诊断。

Abstract

Objective: To investigate the imaging features of pleomorphic xanthoastrocytoma(PXA). Methods: A retrospective study was based on 12 cases of PXA proved by operation and pathology. Ten cases only underwent MRI scanning, 2 cases underwent both CT and MRI scanning. Results: Thirteen lesions were detected in the 12 cases. Six lesions located in the temporal lobe, 4 lesions mainly located in the temporal lobe but involving multiple cerebral lobes, 2 lesions were in the insular lobe and 1 lesion in the frontal lobe. Thirteen lesions could be divided into 3 types of imaging findings: cystic-solid lesion(n=5), cystic lesion with nodule(n=6) and solid nodule(n=2). The solid components and mural nodules enhanced intensely. All the cyst walls had no enhancement in the 5 cystic lesions with nodule. The cerebral piamater closed to the lesion was enhanced in 2 cases. One lesion showed calcification. The apparent diffusion coefficient(ADC) values of solid portions were higher than contralateral tissue. ADC values and relative apparent diffusion coefficient(rADC) values of 2 cases of WHO Ⅲ were obviously lower than 4 cases of WHO Ⅱ. Cho peak ascended and NAA peak declined, with the Cho/NAA values of 0.84 and 1.06 respectively on 1H-MRS of 2 cases. Lac peak was detected in 1 case. Conclusion: There are some imaging characteristics in PXA. Recognizing these characteristics with multi-functional imaging technology of MRI is helpful to improve accuracy of diagnosis.

导出引用

陈小东;刘含秋;陆健;缪小芬;张学琴;梁宏伟;张涛;程斌;姜吉锋. 多形性黄色星形细胞瘤的影像表现[J]. 中国临床医学影像杂志. 2012, 23(8): 533-537

CHEN Xiao-dong;LIU Han-qiu;LU Jian;MIAO Xiao-fen;ZHANG Xue-qin;LIANG Hong-wei;ZHANG Tao;CHENG Bin;JIANG Ji-feng. Imaging findings of pleomorphic xanthoastrocytomas[J]. Journal of China Clinic Medical Imaging. 2012, 23(8): 533-537

中图分类号： Ｒ739.41 Ｒ730.264 Ｒ445.2